Universal label‐free in‐process quantification of influenza virus‐like particles

Virus‐like particles (VLPs) are becoming established as vaccines, in particular for influenza pandemics, increasing the interest in the development of VLPs manufacturing bioprocess. However, for complex VLPs, the analytical tools used for quantification are not yet able to keep up with the bioproces...

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Veröffentlicht in:	Biotechnology journal 2017-08, Vol.12 (8), p.n/a
Hauptverfasser:	Carvalho, Sofia B., Moleirinho, Mafalda G., Wheatley, David, Welsh, John, Gantier, René, Alves, Paula M., Peixoto, Cristina, Carrondo, Manuel J. T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Viral - immunology Antibodies, Viral - isolation & purification Biolayer interferometry technology Downstream process Hemagglutinins - immunology Hemagglutinins - isolation & purification Humans Influenza Vaccines - immunology Influenza Vaccines - therapeutic use Influenza, Human - immunology Influenza, Human - prevention & control Influenza, Human - virology In‐process HA quantification Multivalent VLPs N-Acetylneuraminic Acid - chemistry Octet Vaccines, Virus-Like Particle - immunology Vaccines, Virus-Like Particle - isolation & purification Vaccines, Virus-Like Particle - therapeutic use
Online-Zugang:	Volltext
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