Determination of tocopherols and their metabolites by liquid-chromatography coupled with tandem mass spectrometry in human plasma and serum

Several studies are increasingly underlying the biological role of vitamin E metabolites as bioactive compounds with anti-inflammatory, anti-proliferative and anti-atherogenic activity. A quantitative method for the simultaneous determination in human plasma and serum of vitamin E (α-tocopherol, α-T...

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Veröffentlicht in:	Talanta (Oxford) 2017-08, Vol.170, p.552-561
Hauptverfasser:	Giusepponi, Danilo, Torquato, Pierangelo, Bartolini, Desirée, Piroddi, Marta, Birringer, Marc, Lorkowski, Stefen, Libetta, Carmelo, Cruciani, Gabriele, Moretti, Simone, Saluti, Giorgio, Galli, Francesco, Galarini, Roberta
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Chromatography, Liquid - methods Female Human plasma/serum Humans Limit of Detection Liquid-chromatography tandem-mass spectrometry (LC-MS/MS) Long chain metabolites Male Renal Insufficiency, Chronic - blood Renal Insufficiency, Chronic - metabolism Short chain metabolites Tandem Mass Spectrometry - methods Tocopherols - analysis Tocopherols - blood Tocopherols - metabolism Vitamin E Vitamin E - analysis Vitamin E - blood Vitamin E - metabolism Vitamins - analysis Vitamins - blood Vitamins - metabolism
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