Influence of feeding a fish oil‐containing diet to mature, overweight dogs: Effects on lipid metabolites, postprandial glycaemia and body weight
Summary The objective of this study was to determine the effect of feeding a fish oil (FO)‐containing diet on lipid and protein metabolism, postprandial glycaemia and body weight (BW) of mature, overweight dogs. Seven female dogs were randomly assigned to one of two isonitrogenous and isocaloric die...
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| Veröffentlicht in: | Journal of animal physiology and animal nutrition 2018-02, Vol.102 (1), p.e155-e165 |
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| creator | Godoy, M. R. C. McLeod, K. R. Harmon, D. L. |
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The objective of this study was to determine the effect of feeding a fish oil (FO)‐containing diet on lipid and protein metabolism, postprandial glycaemia and body weight (BW) of mature, overweight dogs. Seven female dogs were randomly assigned to one of two isonitrogenous and isocaloric diets, control (CO) or FO (FO), in a crossover design. Experimental periods were 69 day, separated by a washout period of 30 day. At the beginning of the experiment, and at 30 and 60 day of feeding the experimental diets, the dogs were infused with D‐glucose (2 g/kg BW) through an intravenous catheter. Blood samples were collected for 3 hr to perform a glucose tolerance test. Nitrogen balance measurements began at 06:30 on d 63 of each experimental period and ended at 06:30 on d 69. On d 66 of each period, a single dose (7.5 mg/kg) of 15N‐glycine was administered orally for determination of protein turnover. Incremental area under the curve and glucose concentration at peak did not differ between treatments or among sampling days within treatment. Glucose half‐life tended to decrease (p |
| doi_str_mv | 10.1111/jpn.12723 |
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The objective of this study was to determine the effect of feeding a fish oil (FO)‐containing diet on lipid and protein metabolism, postprandial glycaemia and body weight (BW) of mature, overweight dogs. Seven female dogs were randomly assigned to one of two isonitrogenous and isocaloric diets, control (CO) or FO (FO), in a crossover design. Experimental periods were 69 day, separated by a washout period of 30 day. At the beginning of the experiment, and at 30 and 60 day of feeding the experimental diets, the dogs were infused with D‐glucose (2 g/kg BW) through an intravenous catheter. Blood samples were collected for 3 hr to perform a glucose tolerance test. Nitrogen balance measurements began at 06:30 on d 63 of each experimental period and ended at 06:30 on d 69. On d 66 of each period, a single dose (7.5 mg/kg) of 15N‐glycine was administered orally for determination of protein turnover. Incremental area under the curve and glucose concentration at peak did not differ between treatments or among sampling days within treatment. Glucose half‐life tended to decrease (p < .10) in the FO treatment on day 30 when compared to baseline (day 0). β‐hydroxybutyrate, non‐esterified fatty acid (NEFA) and triglycerides did not differ within or between treatments. Cholesterol decreased (p < .05) on the FO treatment on day 30, 60 and 69 when compared to day 0. High‐density lipoprotein (HDL) decreased (p < .05) in the FO treatment on day 69 when compared to day 0. Body weight, food intake, faecal excretion, DM and N digestibilities, N balance and protein turnover were not different between diets. Overall, FO‐containing diet decreases cholesterol in mature overweight dogs; however, further research is warranted to verify the effects of FO on glucose metabolism.</description><identifier>ISSN: 0931-2439</identifier><identifier>EISSN: 1439-0396</identifier><identifier>DOI: 10.1111/jpn.12723</identifier><identifier>PMID: 28503817</identifier><language>eng</language><publisher>Germany: Wiley Subscription Services, Inc</publisher><subject>Animal Feed - analysis ; Animals ; Blood Glucose ; Body weight ; Cholesterol ; Diet ; Diet - veterinary ; dog ; Dog Diseases - diet therapy ; Dogs ; Esterification ; Excretion ; Fatty acids ; Feeding ; Female ; Fish ; fish oil ; Fish oils ; Fish Oils - pharmacology ; Food intake ; Glucose ; Glucose metabolism ; Glucose tolerance ; Glycine ; High density lipoprotein ; Intravenous administration ; Lipid Metabolism ; lipid metabolites ; Medical instruments ; Metabolism ; Metabolites ; Nitrogen ; Nitrogen balance ; Oils & fats ; Overweight ; Overweight - diet therapy ; Overweight - veterinary ; postprandial glycaemia ; Postprandial Period ; Protein metabolism ; Protein turnover ; Proteins ; Triglycerides</subject><ispartof>Journal of animal physiology and animal nutrition, 2018-02, Vol.102 (1), p.e155-e165</ispartof><rights>2017 Blackwell Verlag GmbH</rights><rights>2017 Blackwell Verlag GmbH.</rights><rights>2018 Blackwell Verlag GmbH</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3533-4d93f6a3a828d0b7d66cce690ba173015f23cddb0d9ba0e1a3dc2053a9daeadf3</citedby><cites>FETCH-LOGICAL-c3533-4d93f6a3a828d0b7d66cce690ba173015f23cddb0d9ba0e1a3dc2053a9daeadf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjpn.12723$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjpn.12723$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28503817$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Godoy, M. R. C.</creatorcontrib><creatorcontrib>McLeod, K. R.</creatorcontrib><creatorcontrib>Harmon, D. L.</creatorcontrib><title>Influence of feeding a fish oil‐containing diet to mature, overweight dogs: Effects on lipid metabolites, postprandial glycaemia and body weight</title><title>Journal of animal physiology and animal nutrition</title><addtitle>J Anim Physiol Anim Nutr (Berl)</addtitle><description>Summary
The objective of this study was to determine the effect of feeding a fish oil (FO)‐containing diet on lipid and protein metabolism, postprandial glycaemia and body weight (BW) of mature, overweight dogs. Seven female dogs were randomly assigned to one of two isonitrogenous and isocaloric diets, control (CO) or FO (FO), in a crossover design. Experimental periods were 69 day, separated by a washout period of 30 day. At the beginning of the experiment, and at 30 and 60 day of feeding the experimental diets, the dogs were infused with D‐glucose (2 g/kg BW) through an intravenous catheter. Blood samples were collected for 3 hr to perform a glucose tolerance test. Nitrogen balance measurements began at 06:30 on d 63 of each experimental period and ended at 06:30 on d 69. On d 66 of each period, a single dose (7.5 mg/kg) of 15N‐glycine was administered orally for determination of protein turnover. Incremental area under the curve and glucose concentration at peak did not differ between treatments or among sampling days within treatment. Glucose half‐life tended to decrease (p < .10) in the FO treatment on day 30 when compared to baseline (day 0). β‐hydroxybutyrate, non‐esterified fatty acid (NEFA) and triglycerides did not differ within or between treatments. Cholesterol decreased (p < .05) on the FO treatment on day 30, 60 and 69 when compared to day 0. High‐density lipoprotein (HDL) decreased (p < .05) in the FO treatment on day 69 when compared to day 0. Body weight, food intake, faecal excretion, DM and N digestibilities, N balance and protein turnover were not different between diets. Overall, FO‐containing diet decreases cholesterol in mature overweight dogs; however, further research is warranted to verify the effects of FO on glucose metabolism.</description><subject>Animal Feed - analysis</subject><subject>Animals</subject><subject>Blood Glucose</subject><subject>Body weight</subject><subject>Cholesterol</subject><subject>Diet</subject><subject>Diet - veterinary</subject><subject>dog</subject><subject>Dog Diseases - diet therapy</subject><subject>Dogs</subject><subject>Esterification</subject><subject>Excretion</subject><subject>Fatty acids</subject><subject>Feeding</subject><subject>Female</subject><subject>Fish</subject><subject>fish oil</subject><subject>Fish oils</subject><subject>Fish Oils - pharmacology</subject><subject>Food intake</subject><subject>Glucose</subject><subject>Glucose metabolism</subject><subject>Glucose tolerance</subject><subject>Glycine</subject><subject>High density lipoprotein</subject><subject>Intravenous administration</subject><subject>Lipid Metabolism</subject><subject>lipid metabolites</subject><subject>Medical instruments</subject><subject>Metabolism</subject><subject>Metabolites</subject><subject>Nitrogen</subject><subject>Nitrogen balance</subject><subject>Oils & fats</subject><subject>Overweight</subject><subject>Overweight - diet therapy</subject><subject>Overweight - veterinary</subject><subject>postprandial glycaemia</subject><subject>Postprandial Period</subject><subject>Protein metabolism</subject><subject>Protein turnover</subject><subject>Proteins</subject><subject>Triglycerides</subject><issn>0931-2439</issn><issn>1439-0396</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc9qFTEUh4Mo9vbqwheQgBsLnTaZ3PmT7qRUrRR1oevhTHJym0smGZOM5e58BPERfRLnOtWF4Nkc-PHxcTg_Qp5xdsbnOd-N_oyXTSkekBXfCFkwIeuHZMWk4EU5B0fkOKUdY7ypWP2YHJVtxUTLmxX5ce2Nm9ArpMFQg6it31KgxqZbGqz7-e27Cj6D9YdcW8w0BzpAniKe0vAV4x3a7W2mOmzTBb0yBlVONHjq7Gg1HTBDH5zNmE7pGFIeI3htwdGt2yvAwQKdA9oHvaeL6gl5ZMAlfHq_1-Tz66tPl2-Lmw9vri9f3RRKVEIUGy2FqUFAW7aa9Y2ua6WwlqwH3gjGK1MKpXXPtOyBIQehVckqAVIDgjZiTV4u3jGGLxOm3A02KXQOPIYpdbyVkvOazx9dkxf_oLswRT9f13F5-OVmw-uZOlkoFUNKEU03RjtA3HecdYeiurmo7ndRM_v83jj1A-q_5J9mZuB8Ae6sw_3_Td27j-8X5S_7vaAs</recordid><startdate>201802</startdate><enddate>201802</enddate><creator>Godoy, M. R. C.</creator><creator>McLeod, K. R.</creator><creator>Harmon, D. L.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>201802</creationdate><title>Influence of feeding a fish oil‐containing diet to mature, overweight dogs: Effects on lipid metabolites, postprandial glycaemia and body weight</title><author>Godoy, M. R. C. ; McLeod, K. R. ; Harmon, D. L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3533-4d93f6a3a828d0b7d66cce690ba173015f23cddb0d9ba0e1a3dc2053a9daeadf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Animal Feed - analysis</topic><topic>Animals</topic><topic>Blood Glucose</topic><topic>Body weight</topic><topic>Cholesterol</topic><topic>Diet</topic><topic>Diet - veterinary</topic><topic>dog</topic><topic>Dog Diseases - diet therapy</topic><topic>Dogs</topic><topic>Esterification</topic><topic>Excretion</topic><topic>Fatty acids</topic><topic>Feeding</topic><topic>Female</topic><topic>Fish</topic><topic>fish oil</topic><topic>Fish oils</topic><topic>Fish Oils - pharmacology</topic><topic>Food intake</topic><topic>Glucose</topic><topic>Glucose metabolism</topic><topic>Glucose tolerance</topic><topic>Glycine</topic><topic>High density lipoprotein</topic><topic>Intravenous administration</topic><topic>Lipid Metabolism</topic><topic>lipid metabolites</topic><topic>Medical instruments</topic><topic>Metabolism</topic><topic>Metabolites</topic><topic>Nitrogen</topic><topic>Nitrogen balance</topic><topic>Oils & fats</topic><topic>Overweight</topic><topic>Overweight - diet therapy</topic><topic>Overweight - veterinary</topic><topic>postprandial glycaemia</topic><topic>Postprandial Period</topic><topic>Protein metabolism</topic><topic>Protein turnover</topic><topic>Proteins</topic><topic>Triglycerides</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Godoy, M. R. C.</creatorcontrib><creatorcontrib>McLeod, K. R.</creatorcontrib><creatorcontrib>Harmon, D. L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of animal physiology and animal nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Godoy, M. R. C.</au><au>McLeod, K. R.</au><au>Harmon, D. L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of feeding a fish oil‐containing diet to mature, overweight dogs: Effects on lipid metabolites, postprandial glycaemia and body weight</atitle><jtitle>Journal of animal physiology and animal nutrition</jtitle><addtitle>J Anim Physiol Anim Nutr (Berl)</addtitle><date>2018-02</date><risdate>2018</risdate><volume>102</volume><issue>1</issue><spage>e155</spage><epage>e165</epage><pages>e155-e165</pages><issn>0931-2439</issn><eissn>1439-0396</eissn><abstract>Summary
The objective of this study was to determine the effect of feeding a fish oil (FO)‐containing diet on lipid and protein metabolism, postprandial glycaemia and body weight (BW) of mature, overweight dogs. Seven female dogs were randomly assigned to one of two isonitrogenous and isocaloric diets, control (CO) or FO (FO), in a crossover design. Experimental periods were 69 day, separated by a washout period of 30 day. At the beginning of the experiment, and at 30 and 60 day of feeding the experimental diets, the dogs were infused with D‐glucose (2 g/kg BW) through an intravenous catheter. Blood samples were collected for 3 hr to perform a glucose tolerance test. Nitrogen balance measurements began at 06:30 on d 63 of each experimental period and ended at 06:30 on d 69. On d 66 of each period, a single dose (7.5 mg/kg) of 15N‐glycine was administered orally for determination of protein turnover. Incremental area under the curve and glucose concentration at peak did not differ between treatments or among sampling days within treatment. Glucose half‐life tended to decrease (p < .10) in the FO treatment on day 30 when compared to baseline (day 0). β‐hydroxybutyrate, non‐esterified fatty acid (NEFA) and triglycerides did not differ within or between treatments. Cholesterol decreased (p < .05) on the FO treatment on day 30, 60 and 69 when compared to day 0. High‐density lipoprotein (HDL) decreased (p < .05) in the FO treatment on day 69 when compared to day 0. Body weight, food intake, faecal excretion, DM and N digestibilities, N balance and protein turnover were not different between diets. Overall, FO‐containing diet decreases cholesterol in mature overweight dogs; however, further research is warranted to verify the effects of FO on glucose metabolism.</abstract><cop>Germany</cop><pub>Wiley Subscription Services, Inc</pub><pmid>28503817</pmid><doi>10.1111/jpn.12723</doi><tpages>11</tpages></addata></record> |
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| source | MEDLINE; Wiley Journals |
| subjects | Animal Feed - analysis Animals Blood Glucose Body weight Cholesterol Diet Diet - veterinary dog Dog Diseases - diet therapy Dogs Esterification Excretion Fatty acids Feeding Female Fish fish oil Fish oils Fish Oils - pharmacology Food intake Glucose Glucose metabolism Glucose tolerance Glycine High density lipoprotein Intravenous administration Lipid Metabolism lipid metabolites Medical instruments Metabolism Metabolites Nitrogen Nitrogen balance Oils & fats Overweight Overweight - diet therapy Overweight - veterinary postprandial glycaemia Postprandial Period Protein metabolism Protein turnover Proteins Triglycerides |
| title | Influence of feeding a fish oil‐containing diet to mature, overweight dogs: Effects on lipid metabolites, postprandial glycaemia and body weight |
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