The ratio of 1/3 linoleic acid to alpha linolenic acid is optimal for oligodendrogenesis of embryonic neural stem cells

•In this study, we investigated the effect of various concentrations and ratios of linoleic acid (LA) and alpha linolenic acid (ALA), which belong respectively to ω-6 and ω-3 PUFAs, on the proliferation and differentiation of eNSCs.•Low or high concentrations of ALA, but not LA, and the ratio of 1:3...

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Veröffentlicht in:	Neuroscience letters 2017-06, Vol.651, p.216-225
Hauptverfasser:	Hejr, Hossein, Ghareghani, Majid, Zibara, Kazem, Ghafari, Maryam, Sadri, Farzad, Salehpour, Zinab, Hamedi, Azadeh, Negintaji, Koresh, Azari, Hassan, Ghanbari, Amir
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Linolenic Acid - pharmacology Animals Astrocytes bHLH Cell Culture Techniques Cell Differentiation Cell Proliferation Cells, Cultured Embryonic neural stem cell Embryonic Stem Cells - physiology Linoleic Acid - pharmacology Mice, Inbred BALB C Oligodendrocyte Precursor Cells - physiology Oligodendrocytes Omega-3 Omega-6
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