Functional analysis of new 3′ untranslated regions genetic variants in genes associated with genetic hypercholesterolemias

Background Familial hypercholesterolemia (FH) is the best-described autosomal dominant genetic hypercholesterolemia (GH). Mutations in candidate genes can explain a high proportion of FH cases, but for many, no causative mutations are detected (designed non-FG-GH), suggesting the existence of additi...

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