MET Exon 14 Skipping Mutations in Lung Adenocarcinoma: Clinicopathologic Implications and Prognostic Values

Response to mesenchymal-epithelial transition (MET) inhibitors in NSCLC with mesenchymal-epithelial transition gene (MET) exon 14 skipping (METex14) has fueled molecular screening efforts and the search for optimal therapies. However, further work is needed to refine the clinicopathologic and progno...

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Veröffentlicht in:	Journal of thoracic oncology 2017-08, Vol.12 (8), p.1233-1246
Hauptverfasser:	Lee, Geun Dong, Lee, Seung Eun, Oh, Doo-Yi, Yu, Dan-bi, Jeong, Hae Min, Kim, Jooseok, Hong, Sungyoul, Jung, Hun Soon, Oh, Ensel, Song, Ji-Young, Lee, Mi-Sook, Kim, Mingi, Jung, Kyungsoo, Kim, Jhingook, Shin, Young Kee, Choi, Yoon-La, Kim, Hyeong Ryul
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - enzymology Adenocarcinoma - genetics Adenocarcinoma - pathology Adenocarcinoma of Lung Aged Asian Continental Ancestry Group - genetics Exons Far East Female Humans Lung adenocarcinoma Lung Neoplasms - enzymology Lung Neoplasms - genetics Lung Neoplasms - pathology Male MET exon 14 skipping MET inhibitor Mutation Prognosis Proto-Oncogene Proteins c-met - genetics siRNA
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