Neurocognitive Risk With PCSK9 Inhibitors: Need for More Robust Evidence

In a pooled analysis of 14 trials of alirocumab, Robinson et al. (1) reported the safety of alirocumab even with very low levels of low-density lipoprotein cholesterol (LDL). They found that 25% of the patients who received alirocumab had an LDL level

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Veröffentlicht in:Journal of the American College of Cardiology 2017-05, Vol.69 (19), p.2468-2469
Hauptverfasser: Khan, Abdur Rahman, Riaz, Haris, Farid, Talha, Bolli, Roberto
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container_end_page 2469
container_issue 19
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container_title Journal of the American College of Cardiology
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creator Khan, Abdur Rahman
Riaz, Haris
Farid, Talha
Bolli, Roberto
description In a pooled analysis of 14 trials of alirocumab, Robinson et al. (1) reported the safety of alirocumab even with very low levels of low-density lipoprotein cholesterol (LDL). They found that 25% of the patients who received alirocumab had an LDL level
doi_str_mv 10.1016/j.jacc.2017.02.063
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source Elsevier ScienceDirect Journals; Alma/SFX Local Collection; EZB Electronic Journals Library
subjects Cardiology
Cardiovascular diseases
Cholesterol
Clinical trials
Cognition
Cognitive ability
Health risks
Heart
Hypercholesterolemia
Incidence
Inhibitor drugs
Kexin
Lipids
Low density lipoprotein
Patients
Populations
Protease
Protease inhibitors
Proteinase
Proteinase inhibitors
Risk
Serine
Side effects
Subtilisin
Therapy
title Neurocognitive Risk With PCSK9 Inhibitors: Need for More Robust Evidence
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