Enantioselective Synthesis of (E)‐δ‐Boryl‐Substituted anti‐Homoallylic Alcohols Using Palladium and a Chiral Phosphoric Acid

(E)‐δ‐Boryl‐substituted anti‐homoallylic alcohols are synthesized in a highly diastereo‐ and enantioselective manner from 1,1‐di(boryl)alk‐3‐enes and aldehydes. Mechanistically, the reaction consists of 1) palladium‐catalyzed double‐bond transposition of the 1,1‐di(boryl)alk‐3‐enes to 1,1‐di(boryl)a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Angewandte Chemie International Edition 2017-06, Vol.56 (24), p.6989-6993
Hauptverfasser:	Miura, Tomoya, Nakahashi, Junki, Murakami, Masahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	allylation asymmetric synthesis homoallylic compounds organocatalysis palladium
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!