High cardiovascular risk in severely obese young children and adolescents
Objective To assess the prevalence of cardiovascular risk factors in severely obese children and adolescents. Methods A nationwide prospective surveillance study was carried out from July 2005 to July 2007 where paediatricians were asked to report all new cases of severe obesity in 2–18-year-old chi...
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creator | van Emmerik, Nathalie M A Renders, Carry M van de Veer, Marije van Buuren, Stef van der Baan-Slootweg, Olga H Kist-van Holthe, Joana E HiraSing, Remy A |
description | Objective To assess the prevalence of cardiovascular risk factors in severely obese children and adolescents. Methods A nationwide prospective surveillance study was carried out from July 2005 to July 2007 where paediatricians were asked to report all new cases of severe obesity in 2–18-year-old children to the Dutch Paediatric Surveillance Unit. Severe obesity is defined by gender and age-dependent cut-off points for body mass index based on Dutch National Growth Studies corresponding to the adult cut-off point of 35 kg/m2. Paediatricians were asked to complete a questionnaire for every severely obese child regarding socio-demographic characteristics and cardiovascular risk factors (blood pressure, fasting blood glucose and lipids). Results In 2005, 2006 and 2007, 94%, 87% and 87%, respectively, of paediatricians in the Netherlands responded to the monthly request from the Dutch Paediatric Surveillance Unit and 500 children with newly diagnosed severe obesity were reported. 72.6% (n=363) of paediatricians responded to a subsequent questionnaire. Cardiovascular risk factor data were available in 255/307 (83%) children who were correctly classified as severely obese. 67% had at least one cardiovascular risk factor (56% hypertension, 14% high blood glucose, 0.7% type 2 diabetes and up to 54% low HDL-cholesterol). Remarkably, 62% of severely obese children aged ≤12 years already had one or more cardiovascular risk factors. Conclusion A high number (2/3) of severely obese children have cardiovascular risk factors. Internationally accepted criteria for defining severe obesity and guidelines for early detection and treatment of severe obesity and comorbidity are urgently needed. |
doi_str_mv | 10.1136/archdischild-2012-301877 |
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Methods A nationwide prospective surveillance study was carried out from July 2005 to July 2007 where paediatricians were asked to report all new cases of severe obesity in 2–18-year-old children to the Dutch Paediatric Surveillance Unit. Severe obesity is defined by gender and age-dependent cut-off points for body mass index based on Dutch National Growth Studies corresponding to the adult cut-off point of 35 kg/m2. Paediatricians were asked to complete a questionnaire for every severely obese child regarding socio-demographic characteristics and cardiovascular risk factors (blood pressure, fasting blood glucose and lipids). Results In 2005, 2006 and 2007, 94%, 87% and 87%, respectively, of paediatricians in the Netherlands responded to the monthly request from the Dutch Paediatric Surveillance Unit and 500 children with newly diagnosed severe obesity were reported. 72.6% (n=363) of paediatricians responded to a subsequent questionnaire. Cardiovascular risk factor data were available in 255/307 (83%) children who were correctly classified as severely obese. 67% had at least one cardiovascular risk factor (56% hypertension, 14% high blood glucose, 0.7% type 2 diabetes and up to 54% low HDL-cholesterol). Remarkably, 62% of severely obese children aged ≤12 years already had one or more cardiovascular risk factors. Conclusion A high number (2/3) of severely obese children have cardiovascular risk factors. Internationally accepted criteria for defining severe obesity and guidelines for early detection and treatment of severe obesity and comorbidity are urgently needed.</description><identifier>ISSN: 0003-9888</identifier><identifier>EISSN: 1468-2044</identifier><identifier>DOI: 10.1136/archdischild-2012-301877</identifier><identifier>PMID: 22826539</identifier><identifier>CODEN: ADCHAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</publisher><subject>Adolescent ; Adolescents ; Age ; Biological and medical sciences ; Blood Glucose ; Blood pressure ; Body Composition ; Body Mass Index ; Cardiology. Vascular system ; Cardiovascular diseases ; Cardiovascular Diseases - blood ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - etiology ; Causes of ; Child ; Child health ; Childhood obesity ; Children ; Children & youth ; Cholesterol ; Cholesterol, HDL - metabolism ; Comorbidity ; Coronary heart disease ; Country of birth ; Diagnosis ; Ethnicity ; Female ; General aspects ; Glucose ; Health aspects ; Health risk assessment ; Health risks ; Heart ; High density lipoprotein ; Humans ; Hypertension ; Lipids ; Low density lipoprotein ; Male ; Medical sciences ; Miscellaneous ; Netherlands - epidemiology ; Obesity ; Obesity - blood ; Obesity - complications ; Obesity - epidemiology ; Obesity in children ; Pediatrics ; Prevalence ; Prevention and actions ; Prospective Studies ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Questionnaires ; Risk Factors ; Sentinel health events ; Sentinel surveillance ; Sociodemographics ; Surveillance ; Teenagers ; Triglycerides ; Triglycerides - metabolism</subject><ispartof>Archives of disease in childhood, 2012-09, Vol.97 (9), p.818-821</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>2015 INIST-CNRS</rights><rights>Copyright: 2012 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b559t-e59199738c1bbbe171a4d5915f15b607f8b0d27805fe8cad88ee6d16cbb6c6913</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://adc.bmj.com/content/97/9/818.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://adc.bmj.com/content/97/9/818.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,780,784,3194,23570,27923,27924,77371,77402</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26331817$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22826539$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van Emmerik, Nathalie M A</creatorcontrib><creatorcontrib>Renders, Carry M</creatorcontrib><creatorcontrib>van de Veer, Marije</creatorcontrib><creatorcontrib>van Buuren, Stef</creatorcontrib><creatorcontrib>van der Baan-Slootweg, Olga H</creatorcontrib><creatorcontrib>Kist-van Holthe, Joana E</creatorcontrib><creatorcontrib>HiraSing, Remy A</creatorcontrib><title>High cardiovascular risk in severely obese young children and adolescents</title><title>Archives of disease in childhood</title><addtitle>Arch Dis Child</addtitle><description>Objective To assess the prevalence of cardiovascular risk factors in severely obese children and adolescents. Methods A nationwide prospective surveillance study was carried out from July 2005 to July 2007 where paediatricians were asked to report all new cases of severe obesity in 2–18-year-old children to the Dutch Paediatric Surveillance Unit. Severe obesity is defined by gender and age-dependent cut-off points for body mass index based on Dutch National Growth Studies corresponding to the adult cut-off point of 35 kg/m2. Paediatricians were asked to complete a questionnaire for every severely obese child regarding socio-demographic characteristics and cardiovascular risk factors (blood pressure, fasting blood glucose and lipids). Results In 2005, 2006 and 2007, 94%, 87% and 87%, respectively, of paediatricians in the Netherlands responded to the monthly request from the Dutch Paediatric Surveillance Unit and 500 children with newly diagnosed severe obesity were reported. 72.6% (n=363) of paediatricians responded to a subsequent questionnaire. Cardiovascular risk factor data were available in 255/307 (83%) children who were correctly classified as severely obese. 67% had at least one cardiovascular risk factor (56% hypertension, 14% high blood glucose, 0.7% type 2 diabetes and up to 54% low HDL-cholesterol). Remarkably, 62% of severely obese children aged ≤12 years already had one or more cardiovascular risk factors. Conclusion A high number (2/3) of severely obese children have cardiovascular risk factors. Internationally accepted criteria for defining severe obesity and guidelines for early detection and treatment of severe obesity and comorbidity are urgently needed.</description><subject>Adolescent</subject><subject>Adolescents</subject><subject>Age</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose</subject><subject>Blood pressure</subject><subject>Body Composition</subject><subject>Body Mass Index</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular diseases</subject><subject>Cardiovascular Diseases - blood</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Causes of</subject><subject>Child</subject><subject>Child health</subject><subject>Childhood obesity</subject><subject>Children</subject><subject>Children & youth</subject><subject>Cholesterol</subject><subject>Cholesterol, HDL - metabolism</subject><subject>Comorbidity</subject><subject>Coronary heart disease</subject><subject>Country of birth</subject><subject>Diagnosis</subject><subject>Ethnicity</subject><subject>Female</subject><subject>General aspects</subject><subject>Glucose</subject><subject>Health aspects</subject><subject>Health risk assessment</subject><subject>Health risks</subject><subject>Heart</subject><subject>High density lipoprotein</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Lipids</subject><subject>Low density lipoprotein</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Netherlands - epidemiology</subject><subject>Obesity</subject><subject>Obesity - blood</subject><subject>Obesity - complications</subject><subject>Obesity - epidemiology</subject><subject>Obesity in children</subject><subject>Pediatrics</subject><subject>Prevalence</subject><subject>Prevention and actions</subject><subject>Prospective Studies</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Questionnaires</subject><subject>Risk Factors</subject><subject>Sentinel health events</subject><subject>Sentinel surveillance</subject><subject>Sociodemographics</subject><subject>Surveillance</subject><subject>Teenagers</subject><subject>Triglycerides</subject><subject>Triglycerides - metabolism</subject><issn>0003-9888</issn><issn>1468-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkU1v1DAQhi0EotvCX0CREBKXgD8SfxyrLdutVLUX4GrZzmQ3W69T7KRi_z0OWVrEhZ4sjZ-Z9515ESoI_kQI459NdNumS27b-aakmNCSYSKFeIEWpOIyl6rqJVpgjFmppJQn6DSlHc6glOw1OqFUUl4ztUBX626zLZyJTdc_mORGb2IRu3RXdKFI8AAR_KHoLSQoDv0YNsVv0QihMKEpTNN7SA7CkN6gV63xCd4e3zP0bfXl63JdXt9eXi3Pr0tb12oooVZEKcGkI9ZaIIKYqsm1uiW15Vi00uKGConrFqQzjZQAvCHcWcsdV4SdoY_z3PvY_xghDXqfLwHemwD9mDSR03TF5DNQSpnESjL2fxQzwTmlCmf0_T_orh9jyDtn7enAqhKTdjlTG-NBd8H1YYCfg-u9hw3ofJLlrT5nmPMckJimypl3sU8pQqvvY7c38ZCl9RS6_jt0PYWu59Bz67ujodHuoXls_JNyBj4cgZyw8W00wXXpieOMEUnEk-cuZa-P_ybeaS6YqPXN96Ve3ay4usBErzPPZt7ud8-3-wv8c9W1</recordid><startdate>20120901</startdate><enddate>20120901</enddate><creator>van Emmerik, Nathalie M A</creator><creator>Renders, Carry M</creator><creator>van de Veer, Marije</creator><creator>van Buuren, Stef</creator><creator>van der Baan-Slootweg, Olga H</creator><creator>Kist-van Holthe, Joana E</creator><creator>HiraSing, Remy A</creator><general>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88B</scope><scope>88E</scope><scope>88I</scope><scope>8A4</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>CJNVE</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0P</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEDU</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>7TS</scope></search><sort><creationdate>20120901</creationdate><title>High cardiovascular risk in severely obese young children and adolescents</title><author>van Emmerik, Nathalie M A ; Renders, Carry M ; van de Veer, Marije ; van Buuren, Stef ; van der Baan-Slootweg, Olga H ; Kist-van Holthe, Joana E ; HiraSing, Remy A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b559t-e59199738c1bbbe171a4d5915f15b607f8b0d27805fe8cad88ee6d16cbb6c6913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Adolescents</topic><topic>Age</topic><topic>Biological and medical sciences</topic><topic>Blood Glucose</topic><topic>Blood pressure</topic><topic>Body Composition</topic><topic>Body Mass Index</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular diseases</topic><topic>Cardiovascular Diseases - blood</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Causes of</topic><topic>Child</topic><topic>Child health</topic><topic>Childhood obesity</topic><topic>Children</topic><topic>Children & youth</topic><topic>Cholesterol</topic><topic>Cholesterol, HDL - metabolism</topic><topic>Comorbidity</topic><topic>Coronary heart disease</topic><topic>Country of birth</topic><topic>Diagnosis</topic><topic>Ethnicity</topic><topic>Female</topic><topic>General aspects</topic><topic>Glucose</topic><topic>Health aspects</topic><topic>Health risk assessment</topic><topic>Health risks</topic><topic>Heart</topic><topic>High density lipoprotein</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Lipids</topic><topic>Low density lipoprotein</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Miscellaneous</topic><topic>Netherlands - epidemiology</topic><topic>Obesity</topic><topic>Obesity - blood</topic><topic>Obesity - complications</topic><topic>Obesity - epidemiology</topic><topic>Obesity in children</topic><topic>Pediatrics</topic><topic>Prevalence</topic><topic>Prevention and actions</topic><topic>Prospective Studies</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Questionnaires</topic><topic>Risk Factors</topic><topic>Sentinel health events</topic><topic>Sentinel surveillance</topic><topic>Sociodemographics</topic><topic>Surveillance</topic><topic>Teenagers</topic><topic>Triglycerides</topic><topic>Triglycerides - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van Emmerik, Nathalie M A</creatorcontrib><creatorcontrib>Renders, Carry M</creatorcontrib><creatorcontrib>van de Veer, Marije</creatorcontrib><creatorcontrib>van Buuren, Stef</creatorcontrib><creatorcontrib>van der Baan-Slootweg, Olga H</creatorcontrib><creatorcontrib>Kist-van Holthe, Joana E</creatorcontrib><creatorcontrib>HiraSing, Remy A</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Education Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Education Periodicals</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Education Collection</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Education Database</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Education</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>Physical Education Index</collection><jtitle>Archives of disease in childhood</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van Emmerik, Nathalie M A</au><au>Renders, Carry M</au><au>van de Veer, Marije</au><au>van Buuren, Stef</au><au>van der Baan-Slootweg, Olga H</au><au>Kist-van Holthe, Joana E</au><au>HiraSing, Remy A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High cardiovascular risk in severely obese young children and adolescents</atitle><jtitle>Archives of disease in childhood</jtitle><addtitle>Arch Dis Child</addtitle><date>2012-09-01</date><risdate>2012</risdate><volume>97</volume><issue>9</issue><spage>818</spage><epage>821</epage><pages>818-821</pages><issn>0003-9888</issn><eissn>1468-2044</eissn><coden>ADCHAK</coden><abstract>Objective To assess the prevalence of cardiovascular risk factors in severely obese children and adolescents. Methods A nationwide prospective surveillance study was carried out from July 2005 to July 2007 where paediatricians were asked to report all new cases of severe obesity in 2–18-year-old children to the Dutch Paediatric Surveillance Unit. Severe obesity is defined by gender and age-dependent cut-off points for body mass index based on Dutch National Growth Studies corresponding to the adult cut-off point of 35 kg/m2. Paediatricians were asked to complete a questionnaire for every severely obese child regarding socio-demographic characteristics and cardiovascular risk factors (blood pressure, fasting blood glucose and lipids). Results In 2005, 2006 and 2007, 94%, 87% and 87%, respectively, of paediatricians in the Netherlands responded to the monthly request from the Dutch Paediatric Surveillance Unit and 500 children with newly diagnosed severe obesity were reported. 72.6% (n=363) of paediatricians responded to a subsequent questionnaire. Cardiovascular risk factor data were available in 255/307 (83%) children who were correctly classified as severely obese. 67% had at least one cardiovascular risk factor (56% hypertension, 14% high blood glucose, 0.7% type 2 diabetes and up to 54% low HDL-cholesterol). Remarkably, 62% of severely obese children aged ≤12 years already had one or more cardiovascular risk factors. Conclusion A high number (2/3) of severely obese children have cardiovascular risk factors. Internationally accepted criteria for defining severe obesity and guidelines for early detection and treatment of severe obesity and comorbidity are urgently needed.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</pub><pmid>22826539</pmid><doi>10.1136/archdischild-2012-301877</doi><tpages>4</tpages></addata></record> |
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subjects | Adolescent Adolescents Age Biological and medical sciences Blood Glucose Blood pressure Body Composition Body Mass Index Cardiology. Vascular system Cardiovascular diseases Cardiovascular Diseases - blood Cardiovascular Diseases - epidemiology Cardiovascular Diseases - etiology Causes of Child Child health Childhood obesity Children Children & youth Cholesterol Cholesterol, HDL - metabolism Comorbidity Coronary heart disease Country of birth Diagnosis Ethnicity Female General aspects Glucose Health aspects Health risk assessment Health risks Heart High density lipoprotein Humans Hypertension Lipids Low density lipoprotein Male Medical sciences Miscellaneous Netherlands - epidemiology Obesity Obesity - blood Obesity - complications Obesity - epidemiology Obesity in children Pediatrics Prevalence Prevention and actions Prospective Studies Public health. Hygiene Public health. Hygiene-occupational medicine Questionnaires Risk Factors Sentinel health events Sentinel surveillance Sociodemographics Surveillance Teenagers Triglycerides Triglycerides - metabolism |
title | High cardiovascular risk in severely obese young children and adolescents |
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