Applications of chemogenomic library screening in drug discovery

Key Points A chemogenomic library is a collection of well-defined pharmacological agents. A hit from such a set in a phenotypic screen suggests that the annotated target or targets of the probe molecules are involved in the phenotypic perturbation. The creation and utility of a number of chemogenomi...

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Veröffentlicht in:Nature reviews. Drug discovery 2017-04, Vol.16 (4), p.285-296
Hauptverfasser: Jones, Lyn H., Bunnage, Mark E.
Format: Artikel
Sprache:eng
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