α-Synuclein in the colon and premotor markers of Parkinson disease in neurologically normal subjects

Extranigral non-motor signs precede the first motor manifestations of Parkinson’s disease by many years in some patients. The presence of α-synuclein deposition within colon tissues in patients with Parkinson’s disease can aid in identifying early neuropathological changes prior to disease onset. In...

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Veröffentlicht in:	Neurological sciences 2017-01, Vol.38 (1), p.171-179
Hauptverfasser:	Kim, Joong-Seok, Park, In-Seok, Park, Hyung-Eun, Kim, Su-Young, Yun, Jung A, Jung, Chan Kwon, Sung, Hye-Young, Lee, Jin-Kwon, Kang, Won-Kyung
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over alpha-Synuclein - metabolism Biomarkers - metabolism Colon - metabolism Colon - pathology Colon - surgery Colonic Neoplasms - metabolism Colonic Neoplasms - pathology Colonic Neoplasms - surgery Female Humans Male Medicine Medicine & Public Health Middle Aged Neurology Neuroradiology Neurosurgery Original Article Parkinson Disease - diagnosis Parkinson Disease - metabolism Phosphorylation Prodromal Symptoms Psychiatry Rectal Neoplasms - metabolism Rectal Neoplasms - pathology Rectal Neoplasms - surgery
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