Single institution experience of paediatric melanoma in Victoria, Australia

Background/Objectives Paediatric melanoma is an uncommon presentation of melanoma that accounts for 3% of all paediatric cancers. The objective was to describe a series of paediatric melanoma cases presenting to a state‐wide tertiary referral service over the past 19 years. Methods A search of the Victorian Melanoma Service database was performed to identify all patients under the age of 20 years diagnosed with melanoma from 1994 to 2013. Histological, demographic and phenotypical information for each patient was collected. Patients were matched against the Victorian Death Registry to identify those who had died. Fisher's exact test was used to examine associations. Melanoma‐specific survival was estimated using the Kaplan–Meier method. Results A total of 65 paediatric melanoma patients were included for analysis, in whom 72.3% of melanomas were diagnosed when they were 16–19 years of age with a mean age at diagnosis of 16 years. The mean Breslow thickness was 1.4 mm. It was greatest (3.4 mm) in the youngest age group (< 12 years of age). Ten patients developed nodal metastatic disease, eight of which progressed to visceral metastatic disease. The 5‐year melanoma‐specific survival rate was 96.8%. Conclusion This is the first descriptive epidemiological study of paediatric melanoma in Victoria. Further large, population‐based, multi‐institutional studies of paediatric melanoma are warranted to provide a clearer understanding of this group of melanoma patients.