Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis
Objective There is a controversy over the influence of obesity on the periodontal treatment outcome in patients with chronic periodontitis (CP). The aim of the present systematic review was to evaluate the efficacy of non-surgical periodontal therapy (NSPT) in the management of CP among obese and no...
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| Veröffentlicht in: | Clinical oral investigations 2016-06, Vol.20 (5), p.903-914 |
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| creator | Akram, Zohaib Safii, Syarida Hasnur Vaithilingam, Rathna Devi Baharuddin, Nor Adinar Javed, Fawad Vohra, Fahim |
| description | Objective
There is a controversy over the influence of obesity on the periodontal treatment outcome in patients with chronic periodontitis (CP). The aim of the present systematic review was to evaluate the efficacy of non-surgical periodontal therapy (NSPT) in the management of CP among obese and non-obese patients.
Materials and methods
The addressed focused question was “What is the efficacy, of NSPT with respect to clinical, radiographic, biochemical, microbiological, and patient-centered outcomes in obese as compared to non-obese chronic periodontitis patients?” Databases were searched from 1977 up to and including December 2014 using relevant key indexing terms. Unpublished data, experimental studies, letters to the editor, review articles, case reports, and commentaries were excluded. Meta-analysis of three studies was performed.
Results
Five clinical studies were included. The total number of patients ranged between 30 and 260 individuals. The mean age of patients was between 42.5 and 48.8 years. In three studies, the clinical periodontal parameters (plaque index (PI), gingival bleeding index (GBI), periodontal pocket depth (PPD), and clinical attachment loss (CAL)) in obese and non-obese patients following NSPT was comparable. Meta-analysis of PPD and CAL among obese and non-obese subjects showed comparable outcomes (PPD
P
= 0.91,
I
2
67.36 %; CAL
P
= 0.87,
I
2
77.16 %). However, in three studies, NSPT resulted in a significantly better clinical periodontal outcome among non-obese subjects than obese subjects. The difference in the levels of serum pro-inflammatory cytokine levels (IL-1β, IL-6, TNF-α, IFN-γ, leptin, adiponectin, and CRP) among obese and non-obese patients following treatment for CP was inconsistent.
Conclusion
It remains unclear whether NSPT has a significantly higher impact on the clinical periodontal outcomes in obese patients than in non-obese patients with chronic periodontitis, given that the number of selected studies was relatively low and the reported findings were inconsistent.
Clinical relevance
Although the effect of obesity on the outcome of NSPT still remains unclear, nevertheless clinicians are prompted to manage obesity prior to and during periodontal treatment |
| doi_str_mv | 10.1007/s00784-016-1793-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1897376951</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1897376951</sourcerecordid><originalsourceid>FETCH-LOGICAL-c471t-def91be9e6c8d0002dc65285ea5a5481fab9424d3a60e8d57150248bb4219a363</originalsourceid><addsrcrecordid>eNqFkctu1jAQhSNERUvhAdggS2zYGHyNbXaoKhepEpuyjhxn8tdVYgc7AeVxeFOcP-WiSqgbe2b8nTOyTlW9oOQNJUS9zeXQAhNaY6oMx-JRdUYFrzFXij4-1gzXRtPT6mnOt4RQUSv-pDplihCpKTurfl72vXfWrSj2KMSA85IOZTCgCZKPXQxzqecbSHZakQ9biUYb7AFGCPOmcjcpBu_-CvzsM7JjDAcUW8iAbOiO3ns32dkXaX6HLMprnmEsA4cSfPfw48iOMFtcdgxr9vlZddLbIcPzu_u8-vrh8vriE7768vHzxfsr7ISiM-6gN7QFA7XTHSGEda6WTEuw0kqhaW9bI5jouK0J6E4qKgkTum0Fo8bymp9Xr3ffKcVvC-S5GX12MAw2QFxyQ7VRXNVG0odRZYiQShpe0Ff30Nu4pPK1jdLGSM6YKRTdKZdizgn6Zkp-tGltKGm2qJs96qZEvbnzRhTNyzvnpR2h-6P4nW0B2A7k8hQOkP5Z_V_XX3w2thE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1789953229</pqid></control><display><type>article</type><title>Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Akram, Zohaib ; Safii, Syarida Hasnur ; Vaithilingam, Rathna Devi ; Baharuddin, Nor Adinar ; Javed, Fawad ; Vohra, Fahim</creator><creatorcontrib>Akram, Zohaib ; Safii, Syarida Hasnur ; Vaithilingam, Rathna Devi ; Baharuddin, Nor Adinar ; Javed, Fawad ; Vohra, Fahim</creatorcontrib><description>Objective
There is a controversy over the influence of obesity on the periodontal treatment outcome in patients with chronic periodontitis (CP). The aim of the present systematic review was to evaluate the efficacy of non-surgical periodontal therapy (NSPT) in the management of CP among obese and non-obese patients.
Materials and methods
The addressed focused question was “What is the efficacy, of NSPT with respect to clinical, radiographic, biochemical, microbiological, and patient-centered outcomes in obese as compared to non-obese chronic periodontitis patients?” Databases were searched from 1977 up to and including December 2014 using relevant key indexing terms. Unpublished data, experimental studies, letters to the editor, review articles, case reports, and commentaries were excluded. Meta-analysis of three studies was performed.
Results
Five clinical studies were included. The total number of patients ranged between 30 and 260 individuals. The mean age of patients was between 42.5 and 48.8 years. In three studies, the clinical periodontal parameters (plaque index (PI), gingival bleeding index (GBI), periodontal pocket depth (PPD), and clinical attachment loss (CAL)) in obese and non-obese patients following NSPT was comparable. Meta-analysis of PPD and CAL among obese and non-obese subjects showed comparable outcomes (PPD
P
= 0.91,
I
2
67.36 %; CAL
P
= 0.87,
I
2
77.16 %). However, in three studies, NSPT resulted in a significantly better clinical periodontal outcome among non-obese subjects than obese subjects. The difference in the levels of serum pro-inflammatory cytokine levels (IL-1β, IL-6, TNF-α, IFN-γ, leptin, adiponectin, and CRP) among obese and non-obese patients following treatment for CP was inconsistent.
Conclusion
It remains unclear whether NSPT has a significantly higher impact on the clinical periodontal outcomes in obese patients than in non-obese patients with chronic periodontitis, given that the number of selected studies was relatively low and the reported findings were inconsistent.
Clinical relevance
Although the effect of obesity on the outcome of NSPT still remains unclear, nevertheless clinicians are prompted to manage obesity prior to and during periodontal treatment</description><identifier>ISSN: 1432-6981</identifier><identifier>EISSN: 1436-3771</identifier><identifier>DOI: 10.1007/s00784-016-1793-4</identifier><identifier>PMID: 27005812</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Chronic Periodontitis - therapy ; Dentistry ; Humans ; Medicine ; Obesity - complications ; Review ; Risk Factors</subject><ispartof>Clinical oral investigations, 2016-06, Vol.20 (5), p.903-914</ispartof><rights>Springer-Verlag Berlin Heidelberg 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-def91be9e6c8d0002dc65285ea5a5481fab9424d3a60e8d57150248bb4219a363</citedby><cites>FETCH-LOGICAL-c471t-def91be9e6c8d0002dc65285ea5a5481fab9424d3a60e8d57150248bb4219a363</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00784-016-1793-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00784-016-1793-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>313,314,776,780,788,27901,27903,27904,41467,42536,51298</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27005812$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Akram, Zohaib</creatorcontrib><creatorcontrib>Safii, Syarida Hasnur</creatorcontrib><creatorcontrib>Vaithilingam, Rathna Devi</creatorcontrib><creatorcontrib>Baharuddin, Nor Adinar</creatorcontrib><creatorcontrib>Javed, Fawad</creatorcontrib><creatorcontrib>Vohra, Fahim</creatorcontrib><title>Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis</title><title>Clinical oral investigations</title><addtitle>Clin Oral Invest</addtitle><addtitle>Clin Oral Investig</addtitle><description>Objective
There is a controversy over the influence of obesity on the periodontal treatment outcome in patients with chronic periodontitis (CP). The aim of the present systematic review was to evaluate the efficacy of non-surgical periodontal therapy (NSPT) in the management of CP among obese and non-obese patients.
Materials and methods
The addressed focused question was “What is the efficacy, of NSPT with respect to clinical, radiographic, biochemical, microbiological, and patient-centered outcomes in obese as compared to non-obese chronic periodontitis patients?” Databases were searched from 1977 up to and including December 2014 using relevant key indexing terms. Unpublished data, experimental studies, letters to the editor, review articles, case reports, and commentaries were excluded. Meta-analysis of three studies was performed.
Results
Five clinical studies were included. The total number of patients ranged between 30 and 260 individuals. The mean age of patients was between 42.5 and 48.8 years. In three studies, the clinical periodontal parameters (plaque index (PI), gingival bleeding index (GBI), periodontal pocket depth (PPD), and clinical attachment loss (CAL)) in obese and non-obese patients following NSPT was comparable. Meta-analysis of PPD and CAL among obese and non-obese subjects showed comparable outcomes (PPD
P
= 0.91,
I
2
67.36 %; CAL
P
= 0.87,
I
2
77.16 %). However, in three studies, NSPT resulted in a significantly better clinical periodontal outcome among non-obese subjects than obese subjects. The difference in the levels of serum pro-inflammatory cytokine levels (IL-1β, IL-6, TNF-α, IFN-γ, leptin, adiponectin, and CRP) among obese and non-obese patients following treatment for CP was inconsistent.
Conclusion
It remains unclear whether NSPT has a significantly higher impact on the clinical periodontal outcomes in obese patients than in non-obese patients with chronic periodontitis, given that the number of selected studies was relatively low and the reported findings were inconsistent.
Clinical relevance
Although the effect of obesity on the outcome of NSPT still remains unclear, nevertheless clinicians are prompted to manage obesity prior to and during periodontal treatment</description><subject>Chronic Periodontitis - therapy</subject><subject>Dentistry</subject><subject>Humans</subject><subject>Medicine</subject><subject>Obesity - complications</subject><subject>Review</subject><subject>Risk Factors</subject><issn>1432-6981</issn><issn>1436-3771</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkctu1jAQhSNERUvhAdggS2zYGHyNbXaoKhepEpuyjhxn8tdVYgc7AeVxeFOcP-WiSqgbe2b8nTOyTlW9oOQNJUS9zeXQAhNaY6oMx-JRdUYFrzFXij4-1gzXRtPT6mnOt4RQUSv-pDplihCpKTurfl72vXfWrSj2KMSA85IOZTCgCZKPXQxzqecbSHZakQ9biUYb7AFGCPOmcjcpBu_-CvzsM7JjDAcUW8iAbOiO3ns32dkXaX6HLMprnmEsA4cSfPfw48iOMFtcdgxr9vlZddLbIcPzu_u8-vrh8vriE7768vHzxfsr7ISiM-6gN7QFA7XTHSGEda6WTEuw0kqhaW9bI5jouK0J6E4qKgkTum0Fo8bymp9Xr3ffKcVvC-S5GX12MAw2QFxyQ7VRXNVG0odRZYiQShpe0Ff30Nu4pPK1jdLGSM6YKRTdKZdizgn6Zkp-tGltKGm2qJs96qZEvbnzRhTNyzvnpR2h-6P4nW0B2A7k8hQOkP5Z_V_XX3w2thE</recordid><startdate>20160601</startdate><enddate>20160601</enddate><creator>Akram, Zohaib</creator><creator>Safii, Syarida Hasnur</creator><creator>Vaithilingam, Rathna Devi</creator><creator>Baharuddin, Nor Adinar</creator><creator>Javed, Fawad</creator><creator>Vohra, Fahim</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>7TS</scope></search><sort><creationdate>20160601</creationdate><title>Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis</title><author>Akram, Zohaib ; Safii, Syarida Hasnur ; Vaithilingam, Rathna Devi ; Baharuddin, Nor Adinar ; Javed, Fawad ; Vohra, Fahim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-def91be9e6c8d0002dc65285ea5a5481fab9424d3a60e8d57150248bb4219a363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Chronic Periodontitis - therapy</topic><topic>Dentistry</topic><topic>Humans</topic><topic>Medicine</topic><topic>Obesity - complications</topic><topic>Review</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Akram, Zohaib</creatorcontrib><creatorcontrib>Safii, Syarida Hasnur</creatorcontrib><creatorcontrib>Vaithilingam, Rathna Devi</creatorcontrib><creatorcontrib>Baharuddin, Nor Adinar</creatorcontrib><creatorcontrib>Javed, Fawad</creatorcontrib><creatorcontrib>Vohra, Fahim</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Physical Education Index</collection><jtitle>Clinical oral investigations</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Akram, Zohaib</au><au>Safii, Syarida Hasnur</au><au>Vaithilingam, Rathna Devi</au><au>Baharuddin, Nor Adinar</au><au>Javed, Fawad</au><au>Vohra, Fahim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis</atitle><jtitle>Clinical oral investigations</jtitle><stitle>Clin Oral Invest</stitle><addtitle>Clin Oral Investig</addtitle><date>2016-06-01</date><risdate>2016</risdate><volume>20</volume><issue>5</issue><spage>903</spage><epage>914</epage><pages>903-914</pages><issn>1432-6981</issn><eissn>1436-3771</eissn><abstract>Objective
There is a controversy over the influence of obesity on the periodontal treatment outcome in patients with chronic periodontitis (CP). The aim of the present systematic review was to evaluate the efficacy of non-surgical periodontal therapy (NSPT) in the management of CP among obese and non-obese patients.
Materials and methods
The addressed focused question was “What is the efficacy, of NSPT with respect to clinical, radiographic, biochemical, microbiological, and patient-centered outcomes in obese as compared to non-obese chronic periodontitis patients?” Databases were searched from 1977 up to and including December 2014 using relevant key indexing terms. Unpublished data, experimental studies, letters to the editor, review articles, case reports, and commentaries were excluded. Meta-analysis of three studies was performed.
Results
Five clinical studies were included. The total number of patients ranged between 30 and 260 individuals. The mean age of patients was between 42.5 and 48.8 years. In three studies, the clinical periodontal parameters (plaque index (PI), gingival bleeding index (GBI), periodontal pocket depth (PPD), and clinical attachment loss (CAL)) in obese and non-obese patients following NSPT was comparable. Meta-analysis of PPD and CAL among obese and non-obese subjects showed comparable outcomes (PPD
P
= 0.91,
I
2
67.36 %; CAL
P
= 0.87,
I
2
77.16 %). However, in three studies, NSPT resulted in a significantly better clinical periodontal outcome among non-obese subjects than obese subjects. The difference in the levels of serum pro-inflammatory cytokine levels (IL-1β, IL-6, TNF-α, IFN-γ, leptin, adiponectin, and CRP) among obese and non-obese patients following treatment for CP was inconsistent.
Conclusion
It remains unclear whether NSPT has a significantly higher impact on the clinical periodontal outcomes in obese patients than in non-obese patients with chronic periodontitis, given that the number of selected studies was relatively low and the reported findings were inconsistent.
Clinical relevance
Although the effect of obesity on the outcome of NSPT still remains unclear, nevertheless clinicians are prompted to manage obesity prior to and during periodontal treatment</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>27005812</pmid><doi>10.1007/s00784-016-1793-4</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Clinical oral investigations, 2016-06, Vol.20 (5), p.903-914 |
| issn | 1432-6981 1436-3771 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1897376951 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Chronic Periodontitis - therapy Dentistry Humans Medicine Obesity - complications Review Risk Factors |
| title | Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis |
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