Metabolic and hormonal consequences of two different meals after a moderate intensity exercise bout in obese prepubertal children

Background/objectives: To investigate the relationship between postprandial nutrient balance, satiety and hormone changes induced by two different meals taken after a moderate intensity exercise bout. Subjects/Methods: Ten prepubertal obese children participated in the study. The experiment was designed as a cross-over study for repeated measures. Each test period lasted five consecutive hours during which the children were under medical supervision. The effects of two isocaloric meals were compared after a moderate intensity exercise (4 multiples of resting metabolic rate, 30 min, cycling): a low-fat/high-carbohydrate meal (meal A) and a high-fat/low-carbohydrate meal (meal B). Pre and postprandial (3 h) substrate oxidation, biochemical parameters, gastrointestinal hormone concentrations and appetite were measured. Results: The main results were: (i) higher fat balance (5.1±5.0 vs −5.0±6.6 g, P =0.001) and lower carbohydrate balance after meal B than A (−9.7±13.3 vs 11.3±18.3 g, P