Glutathione peroxidase 4: a new player in neurodegeneration?

Glutathione peroxidase 4 (GPx4) is an antioxidant enzyme reported as an inhibitor of ferroptosis, a recently discovered non-apoptotic form of cell death. This pathway was initially described in cancer cells and has since been identified in hippocampal and renal cells. In this Perspective, we propose...

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Veröffentlicht in:Molecular psychiatry 2017-03, Vol.22 (3), p.328-335
Hauptverfasser: Cardoso, B R, Hare, D J, Bush, A I, Roberts, B R
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Sprache:eng
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