Evaluation of ST-segment changes during and after maximal exercise tests in one-, two- and three-vessel coronary artery disease

Objective-To relate ECG and heart rate (HR) variables during and after exercise testing with the presence of one-, two- or three-vessel disease defined by angiography. Design-Seventy-three male patients with stable angina pectoris and angiographically verified coronary artery disease underwent a max...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International journal of food sciences and nutrition 2004, Vol.38 (5), p.270-277
Hauptverfasser: Bjurö, Thorvald, Gullestad, Lars, Endresen, Knut, Nordlander, Margareta, Malm, Anders R., Höglund, Lena, Wahlqvist, Inger, Pernow, John
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 277
container_issue 5
container_start_page 270
container_title International journal of food sciences and nutrition
container_volume 38
creator Bjurö, Thorvald
Gullestad, Lars
Endresen, Knut
Nordlander, Margareta
Malm, Anders R.
Höglund, Lena
Wahlqvist, Inger
Pernow, John
description Objective-To relate ECG and heart rate (HR) variables during and after exercise testing with the presence of one-, two- or three-vessel disease defined by angiography. Design-Seventy-three male patients with stable angina pectoris and angiographically verified coronary artery disease underwent a maximal exercise test. From 12-lead ECG recordings and computer averaging ST-amplitude and HR data were measured in consecutive 10-s intervals. Results-In univariate analysis, patients with three-vessel disease had lower maximal exercise capacity, a shorter time to >1 mm ST-depression, more often a clockwise ST HR recovery loop, more frequently a post-exercise downward ST-segment slope, and a greater ST-deficit at 3.5 min after exercise than patients with one-vessel disease. In multivariate analysis, time to >1 mm ST-depression discriminated between patients with three- and one-vessel disease. In patients with an intermediate time to >1 mm ST-depression a clockwise ST HR recovery loop and or a downsloping ST-segment in the post-exercise period were significantly more prevalent in severe vessel disease. Conclusion-Patients with three-vessel disease had a significantly shorter time to >1 mm ST-depression during exercise and more often an abnormal post-exercise ST HR reaction than those with one-vessel disease.
doi_str_mv 10.1080/14017430410021606
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1897373734</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1897373734</sourcerecordid><originalsourceid>FETCH-LOGICAL-c516t-198b45980d5562053de792833ac0a9bd222fe94ffbc47f7104b5bb06a6bf60923</originalsourceid><addsrcrecordid>eNp9kU1v1DAQhiNERZfCD-CCfEIcSBnHH0lEL6gqFKkSB8rZmiTj3ZTEXuyk2z3x1_GyKyqEtPLBlvW8j2b0ZtkrDuccKnjPJfBSCpAcoOAa9JNswaVWuZBl9TRbQK1FXspKn2bPY7wDAK7K8ll2ypXiQkC9yH5d3eMw49R7x7xl327zSMuR3MTaFbolRdbNoXdLhq5jaCcKbMSHfsSB0QOFto_EJopTZH0SOMrfsWnj8z_4tApE-T3FSANrffAOw5ZhSJIt61ISI73ITiwOkV4e7rPs-6er28vr_Obr5y-XH2_yVnE95byuGqnqCjqldAFKdFTWRSUEtoB10xVFYamW1jatLG3JQTaqaUCjbqyGuhBnWb73xg2t58asQ9ohbI3H3hy-fqQXGVUJKXb8mz2_Dv7nnBY0Yx9bGgZ05OdodAkFyKpK4NujIK_qUuyOTCjfo23wMQayf6fgYHaFmv8KTZnXB_3cjNQ9Jg4NJuBiD_TO-jDixoehMxNuBx9sQJcaMuKY_8M_8RXhMK1aDGTu_Bxc6uTIdL8B0YbBCA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1897373734</pqid></control><display><type>article</type><title>Evaluation of ST-segment changes during and after maximal exercise tests in one-, two- and three-vessel coronary artery disease</title><source>MEDLINE</source><source>Taylor &amp; Francis Journals Complete</source><creator>Bjurö, Thorvald ; Gullestad, Lars ; Endresen, Knut ; Nordlander, Margareta ; Malm, Anders R. ; Höglund, Lena ; Wahlqvist, Inger ; Pernow, John</creator><creatorcontrib>Bjurö, Thorvald ; Gullestad, Lars ; Endresen, Knut ; Nordlander, Margareta ; Malm, Anders R. ; Höglund, Lena ; Wahlqvist, Inger ; Pernow, John</creatorcontrib><description>Objective-To relate ECG and heart rate (HR) variables during and after exercise testing with the presence of one-, two- or three-vessel disease defined by angiography. Design-Seventy-three male patients with stable angina pectoris and angiographically verified coronary artery disease underwent a maximal exercise test. From 12-lead ECG recordings and computer averaging ST-amplitude and HR data were measured in consecutive 10-s intervals. Results-In univariate analysis, patients with three-vessel disease had lower maximal exercise capacity, a shorter time to &gt;1 mm ST-depression, more often a clockwise ST HR recovery loop, more frequently a post-exercise downward ST-segment slope, and a greater ST-deficit at 3.5 min after exercise than patients with one-vessel disease. In multivariate analysis, time to &gt;1 mm ST-depression discriminated between patients with three- and one-vessel disease. In patients with an intermediate time to &gt;1 mm ST-depression a clockwise ST HR recovery loop and or a downsloping ST-segment in the post-exercise period were significantly more prevalent in severe vessel disease. Conclusion-Patients with three-vessel disease had a significantly shorter time to &gt;1 mm ST-depression during exercise and more often an abnormal post-exercise ST HR reaction than those with one-vessel disease.</description><identifier>ISSN: 0963-7486</identifier><identifier>ISSN: 1401-7431</identifier><identifier>EISSN: 1465-3478</identifier><identifier>EISSN: 1651-2006</identifier><identifier>DOI: 10.1080/14017430410021606</identifier><identifier>PMID: 15513309</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adult ; Aged ; Angina Pectoris - diagnosis ; Coronary Angiography ; Coronary Artery Disease - classification ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - diagnostic imaging ; Coronary Artery Disease - physiopathology ; Electrocardiography ; Exercise Test ; heart rate recovery ; Humans ; Male ; Middle Aged ; post-exercise ST-segment slope ; Reference Values ; ST/HR recovery loop ; ST/HR slope ; Stroke Volume ; Time Factors ; time to &gt;1 mm ST-depression</subject><ispartof>International journal of food sciences and nutrition, 2004, Vol.38 (5), p.270-277</ispartof><rights>2004 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c516t-198b45980d5562053de792833ac0a9bd222fe94ffbc47f7104b5bb06a6bf60923</citedby><cites>FETCH-LOGICAL-c516t-198b45980d5562053de792833ac0a9bd222fe94ffbc47f7104b5bb06a6bf60923</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/14017430410021606$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/14017430410021606$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>230,314,776,780,881,4010,27902,27903,27904,59623,60412,61197,61378</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15513309$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:1937851$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Bjurö, Thorvald</creatorcontrib><creatorcontrib>Gullestad, Lars</creatorcontrib><creatorcontrib>Endresen, Knut</creatorcontrib><creatorcontrib>Nordlander, Margareta</creatorcontrib><creatorcontrib>Malm, Anders R.</creatorcontrib><creatorcontrib>Höglund, Lena</creatorcontrib><creatorcontrib>Wahlqvist, Inger</creatorcontrib><creatorcontrib>Pernow, John</creatorcontrib><title>Evaluation of ST-segment changes during and after maximal exercise tests in one-, two- and three-vessel coronary artery disease</title><title>International journal of food sciences and nutrition</title><addtitle>Scand Cardiovasc J</addtitle><description>Objective-To relate ECG and heart rate (HR) variables during and after exercise testing with the presence of one-, two- or three-vessel disease defined by angiography. Design-Seventy-three male patients with stable angina pectoris and angiographically verified coronary artery disease underwent a maximal exercise test. From 12-lead ECG recordings and computer averaging ST-amplitude and HR data were measured in consecutive 10-s intervals. Results-In univariate analysis, patients with three-vessel disease had lower maximal exercise capacity, a shorter time to &gt;1 mm ST-depression, more often a clockwise ST HR recovery loop, more frequently a post-exercise downward ST-segment slope, and a greater ST-deficit at 3.5 min after exercise than patients with one-vessel disease. In multivariate analysis, time to &gt;1 mm ST-depression discriminated between patients with three- and one-vessel disease. In patients with an intermediate time to &gt;1 mm ST-depression a clockwise ST HR recovery loop and or a downsloping ST-segment in the post-exercise period were significantly more prevalent in severe vessel disease. Conclusion-Patients with three-vessel disease had a significantly shorter time to &gt;1 mm ST-depression during exercise and more often an abnormal post-exercise ST HR reaction than those with one-vessel disease.</description><subject>Adult</subject><subject>Aged</subject><subject>Angina Pectoris - diagnosis</subject><subject>Coronary Angiography</subject><subject>Coronary Artery Disease - classification</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Coronary Artery Disease - physiopathology</subject><subject>Electrocardiography</subject><subject>Exercise Test</subject><subject>heart rate recovery</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>post-exercise ST-segment slope</subject><subject>Reference Values</subject><subject>ST/HR recovery loop</subject><subject>ST/HR slope</subject><subject>Stroke Volume</subject><subject>Time Factors</subject><subject>time to &gt;1 mm ST-depression</subject><issn>0963-7486</issn><issn>1401-7431</issn><issn>1465-3478</issn><issn>1651-2006</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1v1DAQhiNERZfCD-CCfEIcSBnHH0lEL6gqFKkSB8rZmiTj3ZTEXuyk2z3x1_GyKyqEtPLBlvW8j2b0ZtkrDuccKnjPJfBSCpAcoOAa9JNswaVWuZBl9TRbQK1FXspKn2bPY7wDAK7K8ll2ypXiQkC9yH5d3eMw49R7x7xl327zSMuR3MTaFbolRdbNoXdLhq5jaCcKbMSHfsSB0QOFto_EJopTZH0SOMrfsWnj8z_4tApE-T3FSANrffAOw5ZhSJIt61ISI73ITiwOkV4e7rPs-6er28vr_Obr5y-XH2_yVnE95byuGqnqCjqldAFKdFTWRSUEtoB10xVFYamW1jatLG3JQTaqaUCjbqyGuhBnWb73xg2t58asQ9ohbI3H3hy-fqQXGVUJKXb8mz2_Dv7nnBY0Yx9bGgZ05OdodAkFyKpK4NujIK_qUuyOTCjfo23wMQayf6fgYHaFmv8KTZnXB_3cjNQ9Jg4NJuBiD_TO-jDixoehMxNuBx9sQJcaMuKY_8M_8RXhMK1aDGTu_Bxc6uTIdL8B0YbBCA</recordid><startdate>2004</startdate><enddate>2004</enddate><creator>Bjurö, Thorvald</creator><creator>Gullestad, Lars</creator><creator>Endresen, Knut</creator><creator>Nordlander, Margareta</creator><creator>Malm, Anders R.</creator><creator>Höglund, Lena</creator><creator>Wahlqvist, Inger</creator><creator>Pernow, John</creator><general>Informa UK Ltd</general><general>Taylor &amp; Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope></search><sort><creationdate>2004</creationdate><title>Evaluation of ST-segment changes during and after maximal exercise tests in one-, two- and three-vessel coronary artery disease</title><author>Bjurö, Thorvald ; Gullestad, Lars ; Endresen, Knut ; Nordlander, Margareta ; Malm, Anders R. ; Höglund, Lena ; Wahlqvist, Inger ; Pernow, John</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c516t-198b45980d5562053de792833ac0a9bd222fe94ffbc47f7104b5bb06a6bf60923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Angina Pectoris - diagnosis</topic><topic>Coronary Angiography</topic><topic>Coronary Artery Disease - classification</topic><topic>Coronary Artery Disease - diagnosis</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Coronary Artery Disease - physiopathology</topic><topic>Electrocardiography</topic><topic>Exercise Test</topic><topic>heart rate recovery</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>post-exercise ST-segment slope</topic><topic>Reference Values</topic><topic>ST/HR recovery loop</topic><topic>ST/HR slope</topic><topic>Stroke Volume</topic><topic>Time Factors</topic><topic>time to &gt;1 mm ST-depression</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bjurö, Thorvald</creatorcontrib><creatorcontrib>Gullestad, Lars</creatorcontrib><creatorcontrib>Endresen, Knut</creatorcontrib><creatorcontrib>Nordlander, Margareta</creatorcontrib><creatorcontrib>Malm, Anders R.</creatorcontrib><creatorcontrib>Höglund, Lena</creatorcontrib><creatorcontrib>Wahlqvist, Inger</creatorcontrib><creatorcontrib>Pernow, John</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><jtitle>International journal of food sciences and nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bjurö, Thorvald</au><au>Gullestad, Lars</au><au>Endresen, Knut</au><au>Nordlander, Margareta</au><au>Malm, Anders R.</au><au>Höglund, Lena</au><au>Wahlqvist, Inger</au><au>Pernow, John</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of ST-segment changes during and after maximal exercise tests in one-, two- and three-vessel coronary artery disease</atitle><jtitle>International journal of food sciences and nutrition</jtitle><addtitle>Scand Cardiovasc J</addtitle><date>2004</date><risdate>2004</risdate><volume>38</volume><issue>5</issue><spage>270</spage><epage>277</epage><pages>270-277</pages><issn>0963-7486</issn><issn>1401-7431</issn><eissn>1465-3478</eissn><eissn>1651-2006</eissn><abstract>Objective-To relate ECG and heart rate (HR) variables during and after exercise testing with the presence of one-, two- or three-vessel disease defined by angiography. Design-Seventy-three male patients with stable angina pectoris and angiographically verified coronary artery disease underwent a maximal exercise test. From 12-lead ECG recordings and computer averaging ST-amplitude and HR data were measured in consecutive 10-s intervals. Results-In univariate analysis, patients with three-vessel disease had lower maximal exercise capacity, a shorter time to &gt;1 mm ST-depression, more often a clockwise ST HR recovery loop, more frequently a post-exercise downward ST-segment slope, and a greater ST-deficit at 3.5 min after exercise than patients with one-vessel disease. In multivariate analysis, time to &gt;1 mm ST-depression discriminated between patients with three- and one-vessel disease. In patients with an intermediate time to &gt;1 mm ST-depression a clockwise ST HR recovery loop and or a downsloping ST-segment in the post-exercise period were significantly more prevalent in severe vessel disease. Conclusion-Patients with three-vessel disease had a significantly shorter time to &gt;1 mm ST-depression during exercise and more often an abnormal post-exercise ST HR reaction than those with one-vessel disease.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>15513309</pmid><doi>10.1080/14017430410021606</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0963-7486
ispartof International journal of food sciences and nutrition, 2004, Vol.38 (5), p.270-277
issn 0963-7486
1401-7431
1465-3478
1651-2006
language eng
recordid cdi_proquest_miscellaneous_1897373734
source MEDLINE; Taylor & Francis Journals Complete
subjects Adult
Aged
Angina Pectoris - diagnosis
Coronary Angiography
Coronary Artery Disease - classification
Coronary Artery Disease - diagnosis
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - physiopathology
Electrocardiography
Exercise Test
heart rate recovery
Humans
Male
Middle Aged
post-exercise ST-segment slope
Reference Values
ST/HR recovery loop
ST/HR slope
Stroke Volume
Time Factors
time to >1 mm ST-depression
title Evaluation of ST-segment changes during and after maximal exercise tests in one-, two- and three-vessel coronary artery disease
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T22%3A53%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Evaluation%20of%20ST-segment%20changes%20during%20and%20after%20maximal%20exercise%20tests%20in%20one-,%20two-%20and%20three-vessel%20coronary%20artery%20disease&rft.jtitle=International%20journal%20of%20food%20sciences%20and%20nutrition&rft.au=Bjur%C3%B6,%20Thorvald&rft.date=2004&rft.volume=38&rft.issue=5&rft.spage=270&rft.epage=277&rft.pages=270-277&rft.issn=0963-7486&rft.eissn=1465-3478&rft_id=info:doi/10.1080/14017430410021606&rft_dat=%3Cproquest_pubme%3E1897373734%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1897373734&rft_id=info:pmid/15513309&rfr_iscdi=true