Pre-metastatic niches: organ-specific homes for metastases

Key Points Organs of future metastasis are selectively and actively modified by the primary tumour before metastatic spread has occurred. Tumours induce the formation of microenvironments in distant organs that are conducive to the survival and outgrowth of tumour cells before their arrival at these...

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Veröffentlicht in:	Nature reviews. Cancer 2017-05, Vol.17 (5), p.302-317
Hauptverfasser:	Peinado, Héctor, Zhang, Haiying, Matei, Irina R., Costa-Silva, Bruno, Hoshino, Ayuko, Rodrigues, Goncalo, Psaila, Bethan, Kaplan, Rosandra N., Bromberg, Jacqueline F., Kang, Yibin, Bissell, Mina J., Cox, Thomas R., Giaccia, Amato J., Erler, Janine T., Hiratsuka, Sachie, Ghajar, Cyrus M., Lyden, David
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1857 631/67/322 631/67/327 631/67/580 631/67/70 Animals Biomedicine Cancer Research Humans Neoplasm Metastasis - genetics Neoplasm Metastasis - pathology Neoplasms - genetics Neoplasms - metabolism Neoplasms - pathology Neoplasms - physiopathology Neoplastic Cells, Circulating - metabolism Neoplastic Cells, Circulating - pathology review-article Tumor Microenvironment
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