Human recombinant RNASET2-induced inflammatory response and connective tissue remodeling in the medicinal leech

In recent years, several studies have demonstrated that the RNASET2 gene is involved in the control of tumorigenicity in ovarian cancer cells. Furthermore, a role in establishing a functional cross-talk between cancer cells and the surrounding tumor microenvironment has been unveiled for this gene,...

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Veröffentlicht in:	Cell and tissue research 2017-05, Vol.368 (2), p.337-351
Hauptverfasser:	Baranzini, Nicolò, Pedrini, Edoardo, Girardello, Rossana, Tettamanti, Gianluca, de Eguileor, Magda, Taramelli, Roberto, Acquati, Francesco, Grimaldi, Annalisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - metabolism Animals Biomedical and Life Sciences Biomedicine Cell Proliferation - drug effects Collagen - metabolism Connective Tissue - drug effects Connective Tissue - pathology Cryoultramicrotomy Drug Combinations Enzyme Assays Fluorescent Antibody Technique Genes Hirudinea Hirudo medicinalis - anatomy & histology Hirudo medicinalis - drug effects Hirudo medicinalis - physiology Hirudo medicinalis - ultrastructure Human Genetics Humans Immune response Immune system Inflammation Inflammation - pathology Laminin - metabolism Lipopolysaccharides - pharmacology Macrophages - drug effects Macrophages - metabolism Micrococcus Molecular Medicine Ovarian cancer Proteoglycans - metabolism Proteomics Recombinant Proteins - pharmacology Regular Article Ribonuclease Ribonucleases - pharmacology Tumor Suppressor Proteins - pharmacology Worms
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