Proteomic Profiling Analysis Reveals a Link between Experimental Autoimmune Uveitis and Complement Activation in Rats

Uveitis is an autoimmune disease that usually damages the vision function, leading to poor visual quality in patients. As an autoimmune ocular inflammatory disease, the pathogenesis of uveitis is associated with abnormal expression of some proteins and aberrant regulation of multiple signalling path...

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Veröffentlicht in:	Scandinavian journal of immunology 2017-05, Vol.85 (5), p.331-342
Hauptverfasser:	Guo, D. D., Hu, B., Tang, H. Y., Sun, Y. Y., Liu, B., Tian, Q. M., Bi, H. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmune Diseases - blood Autoimmune Diseases - immunology Autoimmune Diseases - metabolism Chromatography, Liquid Complement Activation Complement C3a - metabolism Complement Membrane Attack Complex - metabolism Disease Models, Animal Enzyme-Linked Immunosorbent Assay Female Humans Protein Interaction Maps Proteome - metabolism Proteomics - methods Rats, Inbred Lew Tandem Mass Spectrometry Uveitis - blood Uveitis - immunology Uveitis - metabolism
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