Sensitivity to House Dust Mites Allergens in Patients with Allergic Asthma in Erzincan Province, Turkey

To investigate the sensitivity of allergic asthma (AA) patients to house dust mites (HDM) by conducting skin tests, measuring total and specific IgE antibodies to Dermatophagoides pteronyssinus and D. farinae mites, and examining HDM fauna in patients' homes. The study included 25 patients with...

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Veröffentlicht in:Türkiye parazitolojii dergisi 2017-03, Vol.41 (1), p.34-41
Hauptverfasser: Zeytun, Erhan, Doğan, Salih, Özçiçek, Fatih, Ünver, Edhem
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creator Zeytun, Erhan
Doğan, Salih
Özçiçek, Fatih
Ünver, Edhem
description To investigate the sensitivity of allergic asthma (AA) patients to house dust mites (HDM) by conducting skin tests, measuring total and specific IgE antibodies to Dermatophagoides pteronyssinus and D. farinae mites, and examining HDM fauna in patients' homes. The study included 25 patients with AA and 31 healthy controls, who were challenged with Der p and Der f allergens; serum levels of allergen-specific lgE and total IgE were measured. Dust samples were collected from the homes of all participants, and mite species and the number of mites per gram of dust were investigated. D. pteronyssinus was found in the homes of 94.7% patients with positive Der p reactions in the skin test (p0.05). D. pteronyssinus-specific IgE was detected in 75% patients in whose homes D. pteronyssinus was also found, while D. farinae-specific IgE was detected in 16.6% patients in whose homes D. farinae was also found. A part of AA patients residing in Erzincan are sensitive to HDM allergens, and high numbers of mites leading to allergic sensitization are found in their homes.
doi_str_mv 10.5152/tpd.2017.5059
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The study included 25 patients with AA and 31 healthy controls, who were challenged with Der p and Der f allergens; serum levels of allergen-specific lgE and total IgE were measured. Dust samples were collected from the homes of all participants, and mite species and the number of mites per gram of dust were investigated. D. pteronyssinus was found in the homes of 94.7% patients with positive Der p reactions in the skin test (p&lt;0.001). D. farinae was found in the homes of 22.2% patients with positive Der f reactions in the skin test (p&gt;0.05). D. pteronyssinus-specific IgE was detected in 75% patients in whose homes D. pteronyssinus was also found, while D. farinae-specific IgE was detected in 16.6% patients in whose homes D. farinae was also found. 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The study included 25 patients with AA and 31 healthy controls, who were challenged with Der p and Der f allergens; serum levels of allergen-specific lgE and total IgE were measured. Dust samples were collected from the homes of all participants, and mite species and the number of mites per gram of dust were investigated. D. pteronyssinus was found in the homes of 94.7% patients with positive Der p reactions in the skin test (p&lt;0.001). D. farinae was found in the homes of 22.2% patients with positive Der f reactions in the skin test (p&gt;0.05). D. pteronyssinus-specific IgE was detected in 75% patients in whose homes D. pteronyssinus was also found, while D. farinae-specific IgE was detected in 16.6% patients in whose homes D. farinae was also found. 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subjects Adolescent
Adult
Aged
Allergens
Allergies
Animals
Antibodies
Antigens, Dermatophagoides - adverse effects
Antigens, Dermatophagoides - immunology
Asthma
Asthma - diagnosis
Asthma - etiology
Case-Control Studies
Child
Dermatophagoides pteronyssinus - anatomy & histology
Dermatophagoides pteronyssinus - immunology
Dust
Dust - analysis
Female
Humans
Immunoglobulin E
Immunoglobulin E - blood
Male
Middle Aged
Peanuts
Serum levels
Skin Tests
Studies
Turkey
Yes-associated protein
Young Adult
title Sensitivity to House Dust Mites Allergens in Patients with Allergic Asthma in Erzincan Province, Turkey
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