Recent thymic emigrants, T regulatory cells, and BAFF level in children with X-linked agammaglobulinaemia in association with chronic respiratory disease

Abstract Background X-linked agammaglobulinaemia (XLA) is a genetic disorder affecting B cell maturation, which is characterised by a low number of B cells, agammaglobulinaemia and increased susceptibility to a variety of bacterial infections. This study was performed to assess T cell subpopulations...

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Veröffentlicht in:	Allergologia et immunopathologia 2018-01, Vol.46 (1), p.58-66
Hauptverfasser:	Sharapova, S.O, Pashchenko, O.E, Guryanova, I.E, Migas, A.A, Kondratenko, I.V, Aleinikova, O.V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Agammaglobulinemia - complications Agammaglobulinemia - immunology Allergy and Immunology B-Cell Activating Factor - metabolism BAFF Bronchitis - complications Bronchitis - immunology Cell Separation Child Child, Preschool Chronic Disease Chronic lung infections Chronic sinusitis Female Flow Cytometry Genetic Diseases, X-Linked - complications Genetic Diseases, X-Linked - immunology Humans Immunologic Memory Immunophenotyping Internal Medicine Male Sinusitis - complications Sinusitis - immunology T cells T-Lymphocyte Subsets - immunology T-Lymphocytes, Regulatory - immunology Thymocytes - immunology X-linked agammaglobulinaemia
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