Pharmacological and Toxicological Study of Maytenus ilicifolia Leaf Extract. Part I – Preclinical Studies

One of the Brazilians medicinal plants most cited in ethnopharmacological surveys for the treatment of ulcers and gastric diseases was evaluated for its efficacy and toxicity. Maytenus ilicifolia leaf extract (MIE) was acutely and chronically (180 days) administered to rats, mice, and dogs. Acute te...

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Veröffentlicht in:	Phytotherapy research 2017-06, Vol.31 (6), p.915-920
Hauptverfasser:	Tabach, Ricardo, Duarte‐Almeida, Joaquim M., Carlini, Elisaldo A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal species Animals antiulcer Body weight loss Brazil chronic study Diseases Dogs Drug Evaluation, Preclinical Effectiveness Estrus cycle experimental studies Female Fertility Fertility - drug effects Food Food consumption Leaves Male Maytenus Maytenus - chemistry Medicinal plants Mice Motor activity Motor task performance Organs Pharmacology Plant extracts Plant Extracts - pharmacology Plant Extracts - toxicity Plant Leaves - chemistry Plants, Medicinal - chemistry Polls & surveys Rats Rats, Wistar Rodents Screening single‐dose toxicity Stomach Ulcer - drug therapy Teratogenicity Toxicity Toxicity testing Toxicity Tests, Acute Toxicity Tests, Chronic Ulcers
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