Numerous Fusiform and Saccular Cerebral Aneurysms in Central Nervous System Lupus Presenting with Ischemic Stroke
Central nervous system (CNS) involvement occurs in up to 50% of patients with systemic lupus erythematosus (SLE). Cerebral aneurysm formation is a rare complication of CNS lupus. The majority of these patients present with subarachnoid hemorrhage. We report a patient with an active SLE flare who pre...
Gespeichert in:
| Veröffentlicht in: | Journal of stroke and cerebrovascular diseases 2017-07, Vol.26 (7), p.e126-e128 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e128 |
|---|---|
| container_issue | 7 |
| container_start_page | e126 |
| container_title | Journal of stroke and cerebrovascular diseases |
| container_volume | 26 |
| creator | Majidi, Shahram, MD Leon Guerrero, Christopher R., MD Gandhy, Shreya, DO Burger, Kathleen M., DO Sigounas, Dimitri, MD |
| description | Central nervous system (CNS) involvement occurs in up to 50% of patients with systemic lupus erythematosus (SLE). Cerebral aneurysm formation is a rare complication of CNS lupus. The majority of these patients present with subarachnoid hemorrhage. We report a patient with an active SLE flare who presented with a recurrent ischemic stroke and was found to have numerous unruptured fusiform and saccular aneurysms in multiple vascular territories. He was treated with high-dose steroid and rituximab along with aspirin and blood pressure control for stroke prevention. |
| doi_str_mv | 10.1016/j.jstrokecerebrovasdis.2017.03.040 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1896411298</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S1052305717301556</els_id><sourcerecordid>1896411298</sourcerecordid><originalsourceid>FETCH-LOGICAL-c459t-19c7fc464536a06dd56330da39a55c0a00cd87a325ea149337ec13739aa5113e3</originalsourceid><addsrcrecordid>eNqVkk1v1DAQhi0Eoh_wF5CPCClhJo7zcUEqK0orrQrSwtlynVnqNB9bT7Jo_z1Ot3BAXDjZnnn9zsyjEeIdQoqAxfs2bXkK4z05CnQbxr3lxnOaAZYpqBRyeCZOUassqTTi83gHnSUKdHkizphbAERd6ZfiJKvyssZKnYqHm7mnMM4sL2f22zH00g6N3Fjn5s4GuXosZTt5MdAcDtyz9EOMDtMSvKGwX_5uDjxRL9fzLj6-BuKY98MP-dNPd_Ka3R313snNY_OvxIut7ZheP53n4vvlp2-rq2T95fP16mKduFzXU4K1K7cuL3KtCgtF0-hCKWisqq3WDiyAa6rSqkyTxbxWqiSHqoxpG4dXpM7F26PvLowPM_Fkes-Ous4OFHs2WNVFjpjVVZR-PEpdGJkDbc0u-N6Gg0EwC3rTmn-hNwt6A8pE9NHkzVO9-ban5o_Fb9ZRsD4KKE699xQMO0-Do8YHcpNpRv9_9T78Zec6P3hnu3s6ELfjHIbI16DhzIDZLMuw7AKWClBHmr8AqDG5rw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1896411298</pqid></control><display><type>article</type><title>Numerous Fusiform and Saccular Cerebral Aneurysms in Central Nervous System Lupus Presenting with Ischemic Stroke</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Majidi, Shahram, MD ; Leon Guerrero, Christopher R., MD ; Gandhy, Shreya, DO ; Burger, Kathleen M., DO ; Sigounas, Dimitri, MD</creator><creatorcontrib>Majidi, Shahram, MD ; Leon Guerrero, Christopher R., MD ; Gandhy, Shreya, DO ; Burger, Kathleen M., DO ; Sigounas, Dimitri, MD</creatorcontrib><description>Central nervous system (CNS) involvement occurs in up to 50% of patients with systemic lupus erythematosus (SLE). Cerebral aneurysm formation is a rare complication of CNS lupus. The majority of these patients present with subarachnoid hemorrhage. We report a patient with an active SLE flare who presented with a recurrent ischemic stroke and was found to have numerous unruptured fusiform and saccular aneurysms in multiple vascular territories. He was treated with high-dose steroid and rituximab along with aspirin and blood pressure control for stroke prevention.</description><identifier>ISSN: 1052-3057</identifier><identifier>EISSN: 1532-8511</identifier><identifier>DOI: 10.1016/j.jstrokecerebrovasdis.2017.03.040</identifier><identifier>PMID: 28479183</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Antihypertensive Agents - therapeutic use ; Aspirin - therapeutic use ; Brain Ischemia - diagnostic imaging ; Brain Ischemia - etiology ; Brain Ischemia - prevention & control ; Cardiovascular ; Cerebral aneurysm ; Cerebral Angiography ; CNS lupus ; Diffusion Magnetic Resonance Imaging ; Humans ; Immunosuppressive Agents - therapeutic use ; Intracranial Aneurysm - diagnostic imaging ; Intracranial Aneurysm - drug therapy ; Intracranial Aneurysm - etiology ; ischemic stroke ; Lupus Vasculitis, Central Nervous System - complications ; Lupus Vasculitis, Central Nervous System - diagnostic imaging ; Lupus Vasculitis, Central Nervous System - drug therapy ; Male ; Neurology ; Platelet Aggregation Inhibitors - therapeutic use ; Recurrence ; Rituximab - therapeutic use ; Steroids - therapeutic use ; Stroke - diagnostic imaging ; Stroke - etiology ; Stroke - prevention & control ; systemic lupus erythematosus ; Treatment Outcome</subject><ispartof>Journal of stroke and cerebrovascular diseases, 2017-07, Vol.26 (7), p.e126-e128</ispartof><rights>National Stroke Association</rights><rights>2017 National Stroke Association</rights><rights>Copyright © 2017 National Stroke Association. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c459t-19c7fc464536a06dd56330da39a55c0a00cd87a325ea149337ec13739aa5113e3</citedby><cites>FETCH-LOGICAL-c459t-19c7fc464536a06dd56330da39a55c0a00cd87a325ea149337ec13739aa5113e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.03.040$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28479183$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Majidi, Shahram, MD</creatorcontrib><creatorcontrib>Leon Guerrero, Christopher R., MD</creatorcontrib><creatorcontrib>Gandhy, Shreya, DO</creatorcontrib><creatorcontrib>Burger, Kathleen M., DO</creatorcontrib><creatorcontrib>Sigounas, Dimitri, MD</creatorcontrib><title>Numerous Fusiform and Saccular Cerebral Aneurysms in Central Nervous System Lupus Presenting with Ischemic Stroke</title><title>Journal of stroke and cerebrovascular diseases</title><addtitle>J Stroke Cerebrovasc Dis</addtitle><description>Central nervous system (CNS) involvement occurs in up to 50% of patients with systemic lupus erythematosus (SLE). Cerebral aneurysm formation is a rare complication of CNS lupus. The majority of these patients present with subarachnoid hemorrhage. We report a patient with an active SLE flare who presented with a recurrent ischemic stroke and was found to have numerous unruptured fusiform and saccular aneurysms in multiple vascular territories. He was treated with high-dose steroid and rituximab along with aspirin and blood pressure control for stroke prevention.</description><subject>Adult</subject><subject>Antihypertensive Agents - therapeutic use</subject><subject>Aspirin - therapeutic use</subject><subject>Brain Ischemia - diagnostic imaging</subject><subject>Brain Ischemia - etiology</subject><subject>Brain Ischemia - prevention & control</subject><subject>Cardiovascular</subject><subject>Cerebral aneurysm</subject><subject>Cerebral Angiography</subject><subject>CNS lupus</subject><subject>Diffusion Magnetic Resonance Imaging</subject><subject>Humans</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Intracranial Aneurysm - diagnostic imaging</subject><subject>Intracranial Aneurysm - drug therapy</subject><subject>Intracranial Aneurysm - etiology</subject><subject>ischemic stroke</subject><subject>Lupus Vasculitis, Central Nervous System - complications</subject><subject>Lupus Vasculitis, Central Nervous System - diagnostic imaging</subject><subject>Lupus Vasculitis, Central Nervous System - drug therapy</subject><subject>Male</subject><subject>Neurology</subject><subject>Platelet Aggregation Inhibitors - therapeutic use</subject><subject>Recurrence</subject><subject>Rituximab - therapeutic use</subject><subject>Steroids - therapeutic use</subject><subject>Stroke - diagnostic imaging</subject><subject>Stroke - etiology</subject><subject>Stroke - prevention & control</subject><subject>systemic lupus erythematosus</subject><subject>Treatment Outcome</subject><issn>1052-3057</issn><issn>1532-8511</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkk1v1DAQhi0Eoh_wF5CPCClhJo7zcUEqK0orrQrSwtlynVnqNB9bT7Jo_z1Ot3BAXDjZnnn9zsyjEeIdQoqAxfs2bXkK4z05CnQbxr3lxnOaAZYpqBRyeCZOUassqTTi83gHnSUKdHkizphbAERd6ZfiJKvyssZKnYqHm7mnMM4sL2f22zH00g6N3Fjn5s4GuXosZTt5MdAcDtyz9EOMDtMSvKGwX_5uDjxRL9fzLj6-BuKY98MP-dNPd_Ka3R313snNY_OvxIut7ZheP53n4vvlp2-rq2T95fP16mKduFzXU4K1K7cuL3KtCgtF0-hCKWisqq3WDiyAa6rSqkyTxbxWqiSHqoxpG4dXpM7F26PvLowPM_Fkes-Ous4OFHs2WNVFjpjVVZR-PEpdGJkDbc0u-N6Gg0EwC3rTmn-hNwt6A8pE9NHkzVO9-ban5o_Fb9ZRsD4KKE699xQMO0-Do8YHcpNpRv9_9T78Zec6P3hnu3s6ELfjHIbI16DhzIDZLMuw7AKWClBHmr8AqDG5rw</recordid><startdate>20170701</startdate><enddate>20170701</enddate><creator>Majidi, Shahram, MD</creator><creator>Leon Guerrero, Christopher R., MD</creator><creator>Gandhy, Shreya, DO</creator><creator>Burger, Kathleen M., DO</creator><creator>Sigounas, Dimitri, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170701</creationdate><title>Numerous Fusiform and Saccular Cerebral Aneurysms in Central Nervous System Lupus Presenting with Ischemic Stroke</title><author>Majidi, Shahram, MD ; Leon Guerrero, Christopher R., MD ; Gandhy, Shreya, DO ; Burger, Kathleen M., DO ; Sigounas, Dimitri, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c459t-19c7fc464536a06dd56330da39a55c0a00cd87a325ea149337ec13739aa5113e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Antihypertensive Agents - therapeutic use</topic><topic>Aspirin - therapeutic use</topic><topic>Brain Ischemia - diagnostic imaging</topic><topic>Brain Ischemia - etiology</topic><topic>Brain Ischemia - prevention & control</topic><topic>Cardiovascular</topic><topic>Cerebral aneurysm</topic><topic>Cerebral Angiography</topic><topic>CNS lupus</topic><topic>Diffusion Magnetic Resonance Imaging</topic><topic>Humans</topic><topic>Immunosuppressive Agents - therapeutic use</topic><topic>Intracranial Aneurysm - diagnostic imaging</topic><topic>Intracranial Aneurysm - drug therapy</topic><topic>Intracranial Aneurysm - etiology</topic><topic>ischemic stroke</topic><topic>Lupus Vasculitis, Central Nervous System - complications</topic><topic>Lupus Vasculitis, Central Nervous System - diagnostic imaging</topic><topic>Lupus Vasculitis, Central Nervous System - drug therapy</topic><topic>Male</topic><topic>Neurology</topic><topic>Platelet Aggregation Inhibitors - therapeutic use</topic><topic>Recurrence</topic><topic>Rituximab - therapeutic use</topic><topic>Steroids - therapeutic use</topic><topic>Stroke - diagnostic imaging</topic><topic>Stroke - etiology</topic><topic>Stroke - prevention & control</topic><topic>systemic lupus erythematosus</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Majidi, Shahram, MD</creatorcontrib><creatorcontrib>Leon Guerrero, Christopher R., MD</creatorcontrib><creatorcontrib>Gandhy, Shreya, DO</creatorcontrib><creatorcontrib>Burger, Kathleen M., DO</creatorcontrib><creatorcontrib>Sigounas, Dimitri, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of stroke and cerebrovascular diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Majidi, Shahram, MD</au><au>Leon Guerrero, Christopher R., MD</au><au>Gandhy, Shreya, DO</au><au>Burger, Kathleen M., DO</au><au>Sigounas, Dimitri, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Numerous Fusiform and Saccular Cerebral Aneurysms in Central Nervous System Lupus Presenting with Ischemic Stroke</atitle><jtitle>Journal of stroke and cerebrovascular diseases</jtitle><addtitle>J Stroke Cerebrovasc Dis</addtitle><date>2017-07-01</date><risdate>2017</risdate><volume>26</volume><issue>7</issue><spage>e126</spage><epage>e128</epage><pages>e126-e128</pages><issn>1052-3057</issn><eissn>1532-8511</eissn><abstract>Central nervous system (CNS) involvement occurs in up to 50% of patients with systemic lupus erythematosus (SLE). Cerebral aneurysm formation is a rare complication of CNS lupus. The majority of these patients present with subarachnoid hemorrhage. We report a patient with an active SLE flare who presented with a recurrent ischemic stroke and was found to have numerous unruptured fusiform and saccular aneurysms in multiple vascular territories. He was treated with high-dose steroid and rituximab along with aspirin and blood pressure control for stroke prevention.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>28479183</pmid><doi>10.1016/j.jstrokecerebrovasdis.2017.03.040</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1052-3057 |
| ispartof | Journal of stroke and cerebrovascular diseases, 2017-07, Vol.26 (7), p.e126-e128 |
| issn | 1052-3057 1532-8511 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1896411298 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adult Antihypertensive Agents - therapeutic use Aspirin - therapeutic use Brain Ischemia - diagnostic imaging Brain Ischemia - etiology Brain Ischemia - prevention & control Cardiovascular Cerebral aneurysm Cerebral Angiography CNS lupus Diffusion Magnetic Resonance Imaging Humans Immunosuppressive Agents - therapeutic use Intracranial Aneurysm - diagnostic imaging Intracranial Aneurysm - drug therapy Intracranial Aneurysm - etiology ischemic stroke Lupus Vasculitis, Central Nervous System - complications Lupus Vasculitis, Central Nervous System - diagnostic imaging Lupus Vasculitis, Central Nervous System - drug therapy Male Neurology Platelet Aggregation Inhibitors - therapeutic use Recurrence Rituximab - therapeutic use Steroids - therapeutic use Stroke - diagnostic imaging Stroke - etiology Stroke - prevention & control systemic lupus erythematosus Treatment Outcome |
| title | Numerous Fusiform and Saccular Cerebral Aneurysms in Central Nervous System Lupus Presenting with Ischemic Stroke |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T20%3A12%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Numerous%20Fusiform%20and%20Saccular%20Cerebral%20Aneurysms%20in%20Central%20Nervous%20System%20Lupus%20Presenting%20with%20Ischemic%20Stroke&rft.jtitle=Journal%20of%20stroke%20and%20cerebrovascular%20diseases&rft.au=Majidi,%20Shahram,%20MD&rft.date=2017-07-01&rft.volume=26&rft.issue=7&rft.spage=e126&rft.epage=e128&rft.pages=e126-e128&rft.issn=1052-3057&rft.eissn=1532-8511&rft_id=info:doi/10.1016/j.jstrokecerebrovasdis.2017.03.040&rft_dat=%3Cproquest_cross%3E1896411298%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1896411298&rft_id=info:pmid/28479183&rft_els_id=1_s2_0_S1052305717301556&rfr_iscdi=true |