Hepatitis C virus may have an entero-hepatic cycle which could be blocked with ezetimibe

Abstract Hepatitis C virus can lead to chronic infection, cirrhosis and hepatocellular carcinoma. With more than 170 million people infected worldwide, eradication remains a challenge even with the revolutionary current direct antiviral agents (DAAs). The risk of resistance, the safety profile in so...

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Veröffentlicht in:	Medical hypotheses 2017-05, Vol.102, p.51-55
Hauptverfasser:	Monrroy, Hugo, López-Lastra, Marcelo, Soza, Alejandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents - administration & dosage Anticholesteremic Agents - administration & dosage Cholesterol - metabolism Ezetimibe - administration & dosage Hepacivirus - drug effects Hepacivirus - physiology Hepatitis C - drug therapy Hepatitis C - virology Humans Internal Medicine Intestines - drug effects Intestines - virology Liver - drug effects Liver - virology Membrane Proteins - antagonists & inhibitors Models, Biological Virus Internalization - drug effects
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