Prodromal Parkinsonism and Neurodegenerative Risk Stratification in REM Sleep Behavior Disorder

Abstract Objectives Rapid eye movement (REM) sleep behavior disorder (RBD) is the most specific marker of prodromal alpha-synucleinopathies. We sought to delineate the baseline clinical characteristics of RBD and evaluate risk stratification models. Methods Clinical assessments were performed in 171...

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Veröffentlicht in:	Sleep (New York, N.Y.) N.Y.), 2017-08, Vol.40 (8)
Hauptverfasser:	Barber, Thomas R, Lawton, Michael, Rolinski, Michal, Evetts, Samuel, Baig, Fahd, Ruffmann, Claudio, Gornall, Aimie, Klein, Johannes C, Lo, Christine, Dennis, Gary, Bandmann, Oliver, Quinnell, Timothy, Zaiwalla, Zenobia, Ben-Shlomo, Yoav, Hu, Michele TM
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antidepressive Agents - pharmacology Anxiety Apathy Behavior disorders Brain diseases Case-Control Studies Depression Female Humans Kinases Male Middle Aged Mutation Mutation - genetics Neurodegeneration Neurological disorders Obesity Parkinson Disease - complications Parkinson Disease - genetics Parkinson Disease - physiopathology Parkinson Disease - psychology Parkinson's disease Phenotype Prodromal Symptoms Quality of Life REM sleep REM Sleep Behavior Disorder - complications REM Sleep Behavior Disorder - genetics REM Sleep Behavior Disorder - physiopathology REM Sleep Behavior Disorder - psychology Risk Assessment Smoking
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