Quercetin suppresses NLRP3 inflammasome activation in epithelial cells triggered by Escherichia coli O157:H7

Inflammatory responses elicited by LRR and PYD domains-containing protein 3 (NLRP3) inflammasome is induced by a wide variety of stress signals including infectious agents and cellular disorders. E. coli O157:H7 causes serious gastrointestinal diseases that results in severe inflammation and oxidati...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Free radical biology & medicine 2017-07, Vol.108, p.760-769
Hauptverfasser:	Xue, Yansong, Du, Min, Zhu, Mei-Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - pharmacology Autophagy Caco-2 Cells Caspase 1 - metabolism Colon - pathology DNA, Mitochondrial - metabolism E. coli O157:H7 Epithelial cells Epithelial Cells - drug effects Epithelial Cells - immunology Escherichia coli Infections - drug therapy Escherichia coli Infections - immunology Escherichia coli O157 - immunology Humans Inflammasome Inflammasomes - metabolism Inflammation Membrane Potential, Mitochondrial Mitochondria NLR Family, Pyrin Domain-Containing 3 Protein - metabolism Polyphenol Quercetin Quercetin - pharmacology Reactive Oxygen Species - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!