Analysis of Normal Hematopoietic Stem and Progenitor Cell Contents in Childhood Acute Leukemia Bone Marrow

Background and Aims Childhood acute leukemias (AL) are characterized by the excessive production of malignant precursor cells at the expense of effective blood cell development. The dominance of leukemic cells over normal progenitors may result in either direct suppression of functional hematopoiesi...

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Veröffentlicht in:	Archives of medical research 2016-11, Vol.47 (8), p.629-643
Hauptverfasser:	Balandrán, Juan Carlos, Vadillo, Eduardo, Dozal, David, Reyes-López, Alfonso, Sandoval-Cabrera, Antonio, Laffont-Ortiz, Merle Denisse, Prieto-Chávez, Jessica L, Vilchis-Ordoñez, Armando, Quintela-Nuñez del Prado, Henry, Mayani, Héctor, Núñez-Enríquez, Juan Carlos, Mejía-Aranguré, Juan Manuel, López-Martínez, Briceida, Jiménez-Hernández, Elva, Pelayo, Rosana
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute lymphoblastic leukemia Bone marrow Bone Marrow - pathology Bone Marrow Cells - pathology Cell Differentiation Child Coculture Techniques Flow Cytometry Hematopoietic Stem Cells - pathology Humans Internal Medicine Lymphoid immune cells Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology ProB-ALL high risk Stem Cells - pathology Stem/progenitor cells
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