Sorting nexin 27 interactome in T‐lymphocytes identifies zona occludens‐2 dynamic redistribution at the immune synapse

T Lymphocyte recognition of antigens leads to the formation of a highly organized structure termed immune synapse (IS) by analogy with the neuronals synapse. Sorting nexin 27 (SNX27) controls the endosomal traffic of PSD95, Dlg1, ZO‐1 (PDZ) domain‐interacting proteins, and its alteration is associat...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2017-08, Vol.18 (8), p.491-504
Hauptverfasser:	Tello‐Lafoz, María, Martínez‐Martínez, Gonzalo, Rodríguez‐Rodríguez, Cristina, Albar, Juan Pablo, Huse, Morgan, Gharbi, Severine, Merida, Isabel
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Biochemistry Cell Line, Tumor cell‐cell interactions endosome Humans immune synapse Immunological Synapses - metabolism Localization Lymphocytes Lymphocytes T membrane traffic Neurological diseases Nexin Postsynaptic density proteins Protein Interaction Maps Protein Transport protein‐protein interactions Proteomics PSD95, Dlg1, ZO‐1 (PDZ) domain sorting nexin (SNX) Sorting Nexins - metabolism T-Lymphocytes - metabolism Vesicles zona occludens‐2 (ZO‐2) Zonula occludens-1 protein Zonula Occludens-2 Protein - metabolism
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