Phosphorylation of Serine 337 of NF-κB p50 Is Critical for DNA Binding

It has been demonstrated that phosphorylation of the p50 subunit of NF-κB is required for efficient DNA binding, yet the specific phospho-residues of p50 have not been determined. In this study, we substituted all of the serine and conserved threonine residues in the p50 Rel homology domain and iden...

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Veröffentlicht in:	The Journal of biological chemistry 2003-11, Vol.278 (46), p.45994-45998
Hauptverfasser:	Hou, Shihe, Guan, Hancheng, Ricciardi, Robert P.
Format:	Artikel
Sprache:	eng
Schlagworte:	p50 protein
Online-Zugang:	Volltext
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