Comprehensive strategy for the design of precision drugs and identification of genetic signature behind proneness of the disease—a pharmacogenomic approach

The proneness of diseases and susceptibility towards drugs vary from person to person. At present, there is a strong demand for the personalization of drugs. The genetic signature behind proneness of the disease has been studied through a comprehensive ‘octopodial approach’. All the genetic variants...

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Veröffentlicht in:	Functional & integrative genomics 2017-07, Vol.17 (4), p.375-385
Hauptverfasser:	Iyer, Preethi M, Karthikeyan, S, Sanjay Kumar, P, Krishnan Namboori, P K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Biochemistry Bioinformatics Biomedical and Life Sciences Biopsy BRCA1 protein BRCA1 Protein - chemistry BRCA1 Protein - genetics Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - genetics Cell Biology Chlorambucil Chlorambucil - chemistry Chlorambucil - pharmacology Drug Design Drug development Drugs Female Genetic Predisposition to Disease Humans Life Sciences Microbial Genetics and Genomics Pharmacogenetics - methods Pharmacogenomics Plant Genetics and Genomics Polymorphism, Single Nucleotide Precision Medicine - methods Review Tamoxifen
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