Optimization of Split-Bolus CT Urography: Effect of Differences in Allocation of Contrast Medium and Prolongation of Imaging Delay
The purpose of this study was to find the optimal allocation ratio of contrast medium (CM) in split-bolus CT urography (CTU) and to investigate the effect of increased imaging delays for synchronous nephrographic-excretory phase imaging. One hundred ninety-two patients were randomly assigned to one...
Gespeichert in:
| Veröffentlicht in: | American journal of roentgenology (1976) 2017-07, Vol.209 (1), p.W10-W17 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | W17 |
|---|---|
| container_issue | 1 |
| container_start_page | W10 |
| container_title | American journal of roentgenology (1976) |
| container_volume | 209 |
| creator | Lee, Dahye Cho, Eun-Suk Kim, Joo Hee Kim, Yong Pyo Lee, Hyeon-Kyeong Yu, Jeong-Sik Chung, Jae-Joon |
| description | The purpose of this study was to find the optimal allocation ratio of contrast medium (CM) in split-bolus CT urography (CTU) and to investigate the effect of increased imaging delays for synchronous nephrographic-excretory phase imaging.
One hundred ninety-two patients were randomly assigned to one of three protocols with different allocation ratios of CM: group A, 30% of CM at first bolus and 70% of CM at second bolus; group B, 70% and 30%; or group C, 50% and 50%. Saline (250 mL) was administered after the first CM bolus. Patients were subdivided by different imaging delay times (8, 10, 12, and 14 minutes). The attenuation values of the renal cortex and medulla were measured, and the opacification and maximal caliber of each segment of the ureter were evaluated.
Renal cortical enhancement was significantly higher in group A (mean ± SD, 145.9 ± 17.5 HU) than group B (120.6 ± 106.3 HU). No significant difference in renal parenchymal enhancement was found with increased imaging delay times. The opacification and maximal caliber of each ureter segment showed no significant difference with different allocation ratios of CM or increased imaging delay times.
A split-bolus CTU protocol with a larger CM volume administered at the second injection and an 8-minute imaging delay was the optimal protocol with regard to opacification of the ureter, renal parenchymal enhancement, and shorter examination time. |
| doi_str_mv | 10.2214/AJR.16.16459 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1894918107</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1894918107</sourcerecordid><originalsourceid>FETCH-LOGICAL-c291t-5620340bb8cd00f85f3a5ac806cf607fcdacbd7df1c26a7912a0dd7c69f627fe3</originalsourceid><addsrcrecordid>eNo9kDtPwzAURi0EoqWwMSOPDKTYTuIkbCUtUFRUBK3EFrl-FCMnDnYylJFfTgql0pW-Oxyd4QBwjtGQEBxdjx5fhph2F8XZAejjOKJBiCN8CPoopDhIUfjWAyfefyCEkjRLjkGPpBENY0L64HteN7rUX6zRtoJWwdfa6Ca4tab1MF_ApbNrx-r3zQ2cKCV5s2XGunudrLj0UFdwZIzle0Fuq8Yx38AnKXRbQlYJ-OyssdV6z0xLttbVGo6lYZtTcKSY8fJstwOwvJss8odgNr-f5qNZwEmGmyCmBIURWq1SLhBSaaxCFjOeIsoVRYnigvGVSITCnFCWZJgwJETCaaYoSZQMB-Dyz1s7-9lK3xSl9lwawyppW1_gNIsynGKUdOjVH8qd9d5JVdROl8xtCoyKbfWiq15gWvxW7_CLnbldlVLs4f_M4Q_1yX67</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1894918107</pqid></control><display><type>article</type><title>Optimization of Split-Bolus CT Urography: Effect of Differences in Allocation of Contrast Medium and Prolongation of Imaging Delay</title><source>American Roentgen Ray Society</source><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Lee, Dahye ; Cho, Eun-Suk ; Kim, Joo Hee ; Kim, Yong Pyo ; Lee, Hyeon-Kyeong ; Yu, Jeong-Sik ; Chung, Jae-Joon</creator><creatorcontrib>Lee, Dahye ; Cho, Eun-Suk ; Kim, Joo Hee ; Kim, Yong Pyo ; Lee, Hyeon-Kyeong ; Yu, Jeong-Sik ; Chung, Jae-Joon</creatorcontrib><description>The purpose of this study was to find the optimal allocation ratio of contrast medium (CM) in split-bolus CT urography (CTU) and to investigate the effect of increased imaging delays for synchronous nephrographic-excretory phase imaging.
One hundred ninety-two patients were randomly assigned to one of three protocols with different allocation ratios of CM: group A, 30% of CM at first bolus and 70% of CM at second bolus; group B, 70% and 30%; or group C, 50% and 50%. Saline (250 mL) was administered after the first CM bolus. Patients were subdivided by different imaging delay times (8, 10, 12, and 14 minutes). The attenuation values of the renal cortex and medulla were measured, and the opacification and maximal caliber of each segment of the ureter were evaluated.
Renal cortical enhancement was significantly higher in group A (mean ± SD, 145.9 ± 17.5 HU) than group B (120.6 ± 106.3 HU). No significant difference in renal parenchymal enhancement was found with increased imaging delay times. The opacification and maximal caliber of each ureter segment showed no significant difference with different allocation ratios of CM or increased imaging delay times.
A split-bolus CTU protocol with a larger CM volume administered at the second injection and an 8-minute imaging delay was the optimal protocol with regard to opacification of the ureter, renal parenchymal enhancement, and shorter examination time.</description><identifier>ISSN: 0361-803X</identifier><identifier>EISSN: 1546-3141</identifier><identifier>DOI: 10.2214/AJR.16.16459</identifier><identifier>PMID: 28463522</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Aged ; Contrast Media - administration & dosage ; Female ; Humans ; Iohexol - administration & dosage ; Iohexol - analogs & derivatives ; Kidney Cortex - diagnostic imaging ; Kidney Diseases - diagnostic imaging ; Male ; Middle Aged ; Radiographic Image Interpretation, Computer-Assisted - methods ; Tomography, X-Ray Computed - methods ; Urography - methods</subject><ispartof>American journal of roentgenology (1976), 2017-07, Vol.209 (1), p.W10-W17</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c291t-5620340bb8cd00f85f3a5ac806cf607fcdacbd7df1c26a7912a0dd7c69f627fe3</citedby><cites>FETCH-LOGICAL-c291t-5620340bb8cd00f85f3a5ac806cf607fcdacbd7df1c26a7912a0dd7c69f627fe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4106,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28463522$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Dahye</creatorcontrib><creatorcontrib>Cho, Eun-Suk</creatorcontrib><creatorcontrib>Kim, Joo Hee</creatorcontrib><creatorcontrib>Kim, Yong Pyo</creatorcontrib><creatorcontrib>Lee, Hyeon-Kyeong</creatorcontrib><creatorcontrib>Yu, Jeong-Sik</creatorcontrib><creatorcontrib>Chung, Jae-Joon</creatorcontrib><title>Optimization of Split-Bolus CT Urography: Effect of Differences in Allocation of Contrast Medium and Prolongation of Imaging Delay</title><title>American journal of roentgenology (1976)</title><addtitle>AJR Am J Roentgenol</addtitle><description>The purpose of this study was to find the optimal allocation ratio of contrast medium (CM) in split-bolus CT urography (CTU) and to investigate the effect of increased imaging delays for synchronous nephrographic-excretory phase imaging.
One hundred ninety-two patients were randomly assigned to one of three protocols with different allocation ratios of CM: group A, 30% of CM at first bolus and 70% of CM at second bolus; group B, 70% and 30%; or group C, 50% and 50%. Saline (250 mL) was administered after the first CM bolus. Patients were subdivided by different imaging delay times (8, 10, 12, and 14 minutes). The attenuation values of the renal cortex and medulla were measured, and the opacification and maximal caliber of each segment of the ureter were evaluated.
Renal cortical enhancement was significantly higher in group A (mean ± SD, 145.9 ± 17.5 HU) than group B (120.6 ± 106.3 HU). No significant difference in renal parenchymal enhancement was found with increased imaging delay times. The opacification and maximal caliber of each ureter segment showed no significant difference with different allocation ratios of CM or increased imaging delay times.
A split-bolus CTU protocol with a larger CM volume administered at the second injection and an 8-minute imaging delay was the optimal protocol with regard to opacification of the ureter, renal parenchymal enhancement, and shorter examination time.</description><subject>Adult</subject><subject>Aged</subject><subject>Contrast Media - administration & dosage</subject><subject>Female</subject><subject>Humans</subject><subject>Iohexol - administration & dosage</subject><subject>Iohexol - analogs & derivatives</subject><subject>Kidney Cortex - diagnostic imaging</subject><subject>Kidney Diseases - diagnostic imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Radiographic Image Interpretation, Computer-Assisted - methods</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Urography - methods</subject><issn>0361-803X</issn><issn>1546-3141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kDtPwzAURi0EoqWwMSOPDKTYTuIkbCUtUFRUBK3EFrl-FCMnDnYylJFfTgql0pW-Oxyd4QBwjtGQEBxdjx5fhph2F8XZAejjOKJBiCN8CPoopDhIUfjWAyfefyCEkjRLjkGPpBENY0L64HteN7rUX6zRtoJWwdfa6Ca4tab1MF_ApbNrx-r3zQ2cKCV5s2XGunudrLj0UFdwZIzle0Fuq8Yx38AnKXRbQlYJ-OyssdV6z0xLttbVGo6lYZtTcKSY8fJstwOwvJss8odgNr-f5qNZwEmGmyCmBIURWq1SLhBSaaxCFjOeIsoVRYnigvGVSITCnFCWZJgwJETCaaYoSZQMB-Dyz1s7-9lK3xSl9lwawyppW1_gNIsynGKUdOjVH8qd9d5JVdROl8xtCoyKbfWiq15gWvxW7_CLnbldlVLs4f_M4Q_1yX67</recordid><startdate>201707</startdate><enddate>201707</enddate><creator>Lee, Dahye</creator><creator>Cho, Eun-Suk</creator><creator>Kim, Joo Hee</creator><creator>Kim, Yong Pyo</creator><creator>Lee, Hyeon-Kyeong</creator><creator>Yu, Jeong-Sik</creator><creator>Chung, Jae-Joon</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201707</creationdate><title>Optimization of Split-Bolus CT Urography: Effect of Differences in Allocation of Contrast Medium and Prolongation of Imaging Delay</title><author>Lee, Dahye ; Cho, Eun-Suk ; Kim, Joo Hee ; Kim, Yong Pyo ; Lee, Hyeon-Kyeong ; Yu, Jeong-Sik ; Chung, Jae-Joon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c291t-5620340bb8cd00f85f3a5ac806cf607fcdacbd7df1c26a7912a0dd7c69f627fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Contrast Media - administration & dosage</topic><topic>Female</topic><topic>Humans</topic><topic>Iohexol - administration & dosage</topic><topic>Iohexol - analogs & derivatives</topic><topic>Kidney Cortex - diagnostic imaging</topic><topic>Kidney Diseases - diagnostic imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Radiographic Image Interpretation, Computer-Assisted - methods</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Urography - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Dahye</creatorcontrib><creatorcontrib>Cho, Eun-Suk</creatorcontrib><creatorcontrib>Kim, Joo Hee</creatorcontrib><creatorcontrib>Kim, Yong Pyo</creatorcontrib><creatorcontrib>Lee, Hyeon-Kyeong</creatorcontrib><creatorcontrib>Yu, Jeong-Sik</creatorcontrib><creatorcontrib>Chung, Jae-Joon</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of roentgenology (1976)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Dahye</au><au>Cho, Eun-Suk</au><au>Kim, Joo Hee</au><au>Kim, Yong Pyo</au><au>Lee, Hyeon-Kyeong</au><au>Yu, Jeong-Sik</au><au>Chung, Jae-Joon</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Optimization of Split-Bolus CT Urography: Effect of Differences in Allocation of Contrast Medium and Prolongation of Imaging Delay</atitle><jtitle>American journal of roentgenology (1976)</jtitle><addtitle>AJR Am J Roentgenol</addtitle><date>2017-07</date><risdate>2017</risdate><volume>209</volume><issue>1</issue><spage>W10</spage><epage>W17</epage><pages>W10-W17</pages><issn>0361-803X</issn><eissn>1546-3141</eissn><abstract>The purpose of this study was to find the optimal allocation ratio of contrast medium (CM) in split-bolus CT urography (CTU) and to investigate the effect of increased imaging delays for synchronous nephrographic-excretory phase imaging.
One hundred ninety-two patients were randomly assigned to one of three protocols with different allocation ratios of CM: group A, 30% of CM at first bolus and 70% of CM at second bolus; group B, 70% and 30%; or group C, 50% and 50%. Saline (250 mL) was administered after the first CM bolus. Patients were subdivided by different imaging delay times (8, 10, 12, and 14 minutes). The attenuation values of the renal cortex and medulla were measured, and the opacification and maximal caliber of each segment of the ureter were evaluated.
Renal cortical enhancement was significantly higher in group A (mean ± SD, 145.9 ± 17.5 HU) than group B (120.6 ± 106.3 HU). No significant difference in renal parenchymal enhancement was found with increased imaging delay times. The opacification and maximal caliber of each ureter segment showed no significant difference with different allocation ratios of CM or increased imaging delay times.
A split-bolus CTU protocol with a larger CM volume administered at the second injection and an 8-minute imaging delay was the optimal protocol with regard to opacification of the ureter, renal parenchymal enhancement, and shorter examination time.</abstract><cop>United States</cop><pmid>28463522</pmid><doi>10.2214/AJR.16.16459</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0361-803X |
| ispartof | American journal of roentgenology (1976), 2017-07, Vol.209 (1), p.W10-W17 |
| issn | 0361-803X 1546-3141 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1894918107 |
| source | American Roentgen Ray Society; MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Aged Contrast Media - administration & dosage Female Humans Iohexol - administration & dosage Iohexol - analogs & derivatives Kidney Cortex - diagnostic imaging Kidney Diseases - diagnostic imaging Male Middle Aged Radiographic Image Interpretation, Computer-Assisted - methods Tomography, X-Ray Computed - methods Urography - methods |
| title | Optimization of Split-Bolus CT Urography: Effect of Differences in Allocation of Contrast Medium and Prolongation of Imaging Delay |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T22%3A08%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Optimization%20of%20Split-Bolus%20CT%20Urography:%20Effect%20of%20Differences%20in%20Allocation%20of%20Contrast%20Medium%20and%20Prolongation%20of%20Imaging%20Delay&rft.jtitle=American%20journal%20of%20roentgenology%20(1976)&rft.au=Lee,%20Dahye&rft.date=2017-07&rft.volume=209&rft.issue=1&rft.spage=W10&rft.epage=W17&rft.pages=W10-W17&rft.issn=0361-803X&rft.eissn=1546-3141&rft_id=info:doi/10.2214/AJR.16.16459&rft_dat=%3Cproquest_cross%3E1894918107%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1894918107&rft_id=info:pmid/28463522&rfr_iscdi=true |