Genotoxic effects of zinc oxide nanoparticles in nasal mucosa cells are antagonized by titanium dioxide nanoparticles

•ZnO-NP-induced toxicity is reduced by TiO2-NPs.•DNA repair capacity after ZnO-NP-induced DNA damage is enhanced by TiO2-NPs.•Interaction of zinc ions and TiO2-NPs may be the reason for toxicity antagonism. Titanium dioxide nanoparticles (TiO2-NPs) and zinc oxide nanoparticles (ZnO-NPs) are often us...

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Veröffentlicht in:	Mutation research. Genetic toxicology and environmental mutagenesis 2017-04, Vol.816-817, p.32-37
Hauptverfasser:	Hackenberg, Stephan, Scherzed, Agmal, Zapp, Angela, Radeloff, Katrin, Ginzkey, Christian, Gehrke, Thomas, Ickrath, Pascal, Kleinsasser, Norbert
Format:	Artikel
Sprache:	eng
Schlagworte:	Antagonism Cells, Cultured Comet Assay DNA Damage - drug effects DNA Repair - drug effects Genotoxicity Humans Hydrogen-Ion Concentration Metal Nanoparticles - chemistry Nanoparticles Nasal Mucosa - cytology Nasal Mucosa - drug effects Titanium - pharmacology Titanium dioxide Zinc - chemistry Zinc oxide Zinc Oxide - toxicity
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