Cell Type- and Promoter-specific Roles of Ser super(18) Phosphorylation in Regulating p53 Responses

Phosphorylation of mouse p53 at Ser super(18) occurs after DNA damage. To determine the physiological roles of this phosphorylation event in p53-dependent DNA damage responses, a Ser super(18) to Ala missense mutation was introduced into the germline of mice. Thymocytes and fibroblasts from the knoc...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 2003-10, Vol.278 (42), p.41028-41033
Hauptverfasser:	Chao, C, Hergenhahn, M, Kaeser, MD, Wu, Z, Saito, S, Iggo, R, Hollstein, M, Appella, E, Xu, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	ATM gene ATM protein
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!