Lutein Enhances Bone Mass by Stimulating Bone Formation and Suppressing Bone Resorption in Growing Mice

Lutein is a member of the xanthophyll family of carotenoids, which are known to prevent hypoxia-induced cell damage in the eye by removing free radicals. However, its role in other tissues is controversial, and the effects of lutein on bone tissues are unknown. To identify a possible role of lutein...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2017/05/01, Vol.40(5), pp.716-721
Hauptverfasser:	Takeda, Hiroshi, Tominari, Tsukasa, Hirata, Michiko, Watanabe, Kenta, Matsumoto, Chiho, Grundler, Florian M. W., Inada, Masaki, Miyaura, Chisato
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry Absorptiometry, Photon Animals Bone and Bones - anatomy & histology Bone and Bones - diagnostic imaging Bone density Bone Density - drug effects Bone Development - drug effects bone formation Bone growth Bone marrow Bone mass Bone mineral density Bone resorption Bone Resorption - prevention & control Bone turnover Calcification, Physiologic - drug effects Calcitriol - antagonists & inhibitors Calcitriol - pharmacology Calvaria Carotenoids Cell culture Cells, Cultured Computed tomography Cortical bone Dual energy X-ray absorptiometry Eye Femur Femur - anatomy & histology Femur - drug effects Free radicals growing mouse Hypoxia lutein Lutein - pharmacology Lutein - therapeutic use Macrophages Male Mice NF-kappa B - antagonists & inhibitors Nodules Organ culture Osteoblasts - drug effects Osteogenesis RANK Ligand - antagonists & inhibitors Tissues Tomography, X-Ray Computed Vitamin D Vitamin D3
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