Plasma DNA and RNA differentially impact coagulation during abdominal sepsis – an explorative study

Abstract Background Cell-free DNA (cfDNA) and extracellular RNA (exRNA) are both suspected to activate coagulation cascades in sepsis. Therefore, our study investigated the influence of plasmatic nucleic acids on coagulation in septic patients in comparison to patients after major abdominal surgery....

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Veröffentlicht in:The Journal of surgical research 2017-04, Vol.210, p.231-243
Hauptverfasser: Schneck, Emmanuel, Samara, Omar, Koch, Christian, Hecker, Andreas, Padberg, Winfried, Lichtenstern, Christoph, Weigand, Markus Alexander, Uhle, Florian, Ph.D
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Sprache:eng
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