Combinatorial Strategy to Identify Fluorescent Probes for Biothiol and Thiophenol Based on Diversified Pyrimidine Moieties and Their Biological Applications

We present a feasible paradigm of developing original fluorescent probes for target biomolecules via combinatorial chemistry. In this developmental program, pyrimidine moieties were investigated and optimized as unique recognition units for thiols for the first time through a parallel synthesis in c...

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Veröffentlicht in:	Analytical chemistry (Washington) 2017-03, Vol.89 (5), p.3015-3020
Hauptverfasser:	Xie, Xilei, Li, Mengmeng, Tang, Fuyan, Li, Yong, Zhang, Leilei, Jiao, Xiaoyun, Wang, Xu, Tang, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Apoptosis Biomolecules Cells Cells (biology) Combinatorics Fluorescence Organic chemicals Oxidative stress Pyrimidines Recognition Thiophenol
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