Injury risk prediction from computational simulations of ocular blast loading
A predictive Lagrangian–Eulerian finite element eye model was used to analyze 2.27 and 0.45 kg trinitrotoluene equivalent blasts detonated from 24 different locations. Free air and ground level blasts were simulated directly in front of the eye and at lateral offset locations with box, average, less...
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description | A predictive Lagrangian–Eulerian finite element eye model was used to analyze 2.27 and 0.45 kg trinitrotoluene equivalent blasts detonated from 24 different locations. Free air and ground level blasts were simulated directly in front of the eye and at lateral offset locations with box, average, less protective, and more protective orbital anthropometries, resulting in 96 simulations. Injury risk curves were developed for hyphema, lens dislocation, retinal damage, and globe rupture from experimental and computational data to compute risk from corneoscleral stress and intra-ocular pressure computational outputs. Corneoscleral stress, intra-ocular pressure, and injury risks increased when the blast size was larger and located nearer to the eye. Risks ranged from 20–100 % for hyphema, 1–100 % for lens dislocation, 2–100 % for retinal damage, and 0–98 % for globe rupture depending on the blast condition. Orbital geometry affected the stresses, pressures, and associated ocular injury risks of the blast conditions simulated. Orbital geometries that more fully surrounded the eye such as the more protective orbit tended to produce higher corneoscleral stresses and compression of the eye against the surrounding rigid orbit contributing to high stresses as the blast wave propagated. However, the more protective orbit tended to produce lower intra-ocular pressures in comparison with the other three orbital geometries which may indicate that the more protective orbit inhibits propagation of the blast wave and reduces ocular loading. Results of this parametric computational study of ocular blast loading are valuable to the design of eye protection equipment and the mitigation of blast-related eye injuries. |
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Free air and ground level blasts were simulated directly in front of the eye and at lateral offset locations with box, average, less protective, and more protective orbital anthropometries, resulting in 96 simulations. Injury risk curves were developed for hyphema, lens dislocation, retinal damage, and globe rupture from experimental and computational data to compute risk from corneoscleral stress and intra-ocular pressure computational outputs. Corneoscleral stress, intra-ocular pressure, and injury risks increased when the blast size was larger and located nearer to the eye. Risks ranged from 20–100 % for hyphema, 1–100 % for lens dislocation, 2–100 % for retinal damage, and 0–98 % for globe rupture depending on the blast condition. Orbital geometry affected the stresses, pressures, and associated ocular injury risks of the blast conditions simulated. Orbital geometries that more fully surrounded the eye such as the more protective orbit tended to produce higher corneoscleral stresses and compression of the eye against the surrounding rigid orbit contributing to high stresses as the blast wave propagated. However, the more protective orbit tended to produce lower intra-ocular pressures in comparison with the other three orbital geometries which may indicate that the more protective orbit inhibits propagation of the blast wave and reduces ocular loading. Results of this parametric computational study of ocular blast loading are valuable to the design of eye protection equipment and the mitigation of blast-related eye injuries.</description><identifier>ISSN: 1617-7959</identifier><identifier>EISSN: 1617-7940</identifier><identifier>DOI: 10.1007/s10237-016-0830-1</identifier><identifier>PMID: 27644440</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Biological and Medical Physics ; Biomedical Engineering and Bioengineering ; Biophysics ; Blast Injuries - prevention & control ; Computation ; Computer based modeling ; Computer Simulation ; Engineering ; Eye ; Eye injuries ; Eye Injuries - prevention & control ; Eyes ; Eyes & eyesight ; Health risks ; Humans ; Injuries ; Mathematical models ; Models, Theoretical ; Orbit - anatomy & histology ; Original Paper ; Risk ; Risk Assessment - methods ; Risk factors ; Space life sciences ; Stresses ; Theoretical and Applied Mechanics</subject><ispartof>Biomechanics and modeling in mechanobiology, 2017-04, Vol.16 (2), p.463-477</ispartof><rights>Springer-Verlag Berlin Heidelberg 2016</rights><rights>Biomechanics and Modeling in Mechanobiology is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c504t-ae030f620c5360932200c81d6fbe62bc7b677cee22ec1da14a1bd805600e4a7d3</citedby><cites>FETCH-LOGICAL-c504t-ae030f620c5360932200c81d6fbe62bc7b677cee22ec1da14a1bd805600e4a7d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10237-016-0830-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10237-016-0830-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27644440$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Weaver, Ashley A.</creatorcontrib><creatorcontrib>Stitzel, Sarah M.</creatorcontrib><creatorcontrib>Stitzel, Joel D.</creatorcontrib><title>Injury risk prediction from computational simulations of ocular blast loading</title><title>Biomechanics and modeling in mechanobiology</title><addtitle>Biomech Model Mechanobiol</addtitle><addtitle>Biomech Model Mechanobiol</addtitle><description>A predictive Lagrangian–Eulerian finite element eye model was used to analyze 2.27 and 0.45 kg trinitrotoluene equivalent blasts detonated from 24 different locations. Free air and ground level blasts were simulated directly in front of the eye and at lateral offset locations with box, average, less protective, and more protective orbital anthropometries, resulting in 96 simulations. Injury risk curves were developed for hyphema, lens dislocation, retinal damage, and globe rupture from experimental and computational data to compute risk from corneoscleral stress and intra-ocular pressure computational outputs. Corneoscleral stress, intra-ocular pressure, and injury risks increased when the blast size was larger and located nearer to the eye. Risks ranged from 20–100 % for hyphema, 1–100 % for lens dislocation, 2–100 % for retinal damage, and 0–98 % for globe rupture depending on the blast condition. Orbital geometry affected the stresses, pressures, and associated ocular injury risks of the blast conditions simulated. Orbital geometries that more fully surrounded the eye such as the more protective orbit tended to produce higher corneoscleral stresses and compression of the eye against the surrounding rigid orbit contributing to high stresses as the blast wave propagated. However, the more protective orbit tended to produce lower intra-ocular pressures in comparison with the other three orbital geometries which may indicate that the more protective orbit inhibits propagation of the blast wave and reduces ocular loading. Results of this parametric computational study of ocular blast loading are valuable to the design of eye protection equipment and the mitigation of blast-related eye injuries.</description><subject>Biological and Medical Physics</subject><subject>Biomedical Engineering and Bioengineering</subject><subject>Biophysics</subject><subject>Blast Injuries - prevention & control</subject><subject>Computation</subject><subject>Computer based modeling</subject><subject>Computer Simulation</subject><subject>Engineering</subject><subject>Eye</subject><subject>Eye injuries</subject><subject>Eye Injuries - prevention & control</subject><subject>Eyes</subject><subject>Eyes & eyesight</subject><subject>Health risks</subject><subject>Humans</subject><subject>Injuries</subject><subject>Mathematical models</subject><subject>Models, Theoretical</subject><subject>Orbit - anatomy & histology</subject><subject>Original Paper</subject><subject>Risk</subject><subject>Risk Assessment - methods</subject><subject>Risk factors</subject><subject>Space life sciences</subject><subject>Stresses</subject><subject>Theoretical and Applied Mechanics</subject><issn>1617-7959</issn><issn>1617-7940</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkctKxTAQhoMo3h_AjQTcuKnOJG2SLkW8geJG1yFNU-mxbY5Ju_DtTT1HEUEwm2SSb_7AfIQcIZwhgDyPCIzLDFBkoDhkuEF2UaDMZJnD5ve5KHfIXowLAAZc8W2yw6TI04Jd8nA3LKbwTkMbX-kyuLq1Y-sH2gTfU-v75TSa-cJ0NLb91H0WkfqGepuqQKvOxJF23tTt8HJAthrTRXe43vfJ8_XV0-Vtdv94c3d5cZ_ZAvIxMw44NIKBLbiAkjMGYBXWoqmcYJWVlZDSOseYs1gbzA1WtYJCALjcyJrvk9NV7jL4t8nFUfdttK7rzOD8FDWqkiuFRZ7_A1UohWIc_oEWpeS5UEVCT36hCz-FNKWZkhLScMuZwhVlg48xuEYvQ9ub8K4R9GxQrwzqZFDPBjWmnuN18lT1rv7u-FKWALYCYnoaXlz48fWfqR8ZwqTZ</recordid><startdate>20170401</startdate><enddate>20170401</enddate><creator>Weaver, Ashley A.</creator><creator>Stitzel, Sarah M.</creator><creator>Stitzel, Joel D.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7QP</scope><scope>7TB</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>M7S</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>Q9U</scope><scope>S0W</scope><scope>7X8</scope></search><sort><creationdate>20170401</creationdate><title>Injury risk prediction from computational simulations of ocular blast loading</title><author>Weaver, Ashley A. ; Stitzel, Sarah M. ; Stitzel, Joel D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c504t-ae030f620c5360932200c81d6fbe62bc7b677cee22ec1da14a1bd805600e4a7d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Biological and Medical Physics</topic><topic>Biomedical Engineering and Bioengineering</topic><topic>Biophysics</topic><topic>Blast Injuries - prevention & control</topic><topic>Computation</topic><topic>Computer based modeling</topic><topic>Computer Simulation</topic><topic>Engineering</topic><topic>Eye</topic><topic>Eye injuries</topic><topic>Eye Injuries - prevention & control</topic><topic>Eyes</topic><topic>Eyes & eyesight</topic><topic>Health risks</topic><topic>Humans</topic><topic>Injuries</topic><topic>Mathematical models</topic><topic>Models, Theoretical</topic><topic>Orbit - anatomy & histology</topic><topic>Original Paper</topic><topic>Risk</topic><topic>Risk Assessment - methods</topic><topic>Risk factors</topic><topic>Space life sciences</topic><topic>Stresses</topic><topic>Theoretical and Applied Mechanics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weaver, Ashley A.</creatorcontrib><creatorcontrib>Stitzel, Sarah M.</creatorcontrib><creatorcontrib>Stitzel, Joel D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>ProQuest Central Basic</collection><collection>DELNET Engineering & Technology Collection</collection><collection>MEDLINE - Academic</collection><jtitle>Biomechanics and modeling in mechanobiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Weaver, Ashley A.</au><au>Stitzel, Sarah M.</au><au>Stitzel, Joel D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Injury risk prediction from computational simulations of ocular blast loading</atitle><jtitle>Biomechanics and modeling in mechanobiology</jtitle><stitle>Biomech Model Mechanobiol</stitle><addtitle>Biomech Model Mechanobiol</addtitle><date>2017-04-01</date><risdate>2017</risdate><volume>16</volume><issue>2</issue><spage>463</spage><epage>477</epage><pages>463-477</pages><issn>1617-7959</issn><eissn>1617-7940</eissn><abstract>A predictive Lagrangian–Eulerian finite element eye model was used to analyze 2.27 and 0.45 kg trinitrotoluene equivalent blasts detonated from 24 different locations. Free air and ground level blasts were simulated directly in front of the eye and at lateral offset locations with box, average, less protective, and more protective orbital anthropometries, resulting in 96 simulations. Injury risk curves were developed for hyphema, lens dislocation, retinal damage, and globe rupture from experimental and computational data to compute risk from corneoscleral stress and intra-ocular pressure computational outputs. Corneoscleral stress, intra-ocular pressure, and injury risks increased when the blast size was larger and located nearer to the eye. Risks ranged from 20–100 % for hyphema, 1–100 % for lens dislocation, 2–100 % for retinal damage, and 0–98 % for globe rupture depending on the blast condition. Orbital geometry affected the stresses, pressures, and associated ocular injury risks of the blast conditions simulated. Orbital geometries that more fully surrounded the eye such as the more protective orbit tended to produce higher corneoscleral stresses and compression of the eye against the surrounding rigid orbit contributing to high stresses as the blast wave propagated. However, the more protective orbit tended to produce lower intra-ocular pressures in comparison with the other three orbital geometries which may indicate that the more protective orbit inhibits propagation of the blast wave and reduces ocular loading. Results of this parametric computational study of ocular blast loading are valuable to the design of eye protection equipment and the mitigation of blast-related eye injuries.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>27644440</pmid><doi>10.1007/s10237-016-0830-1</doi><tpages>15</tpages></addata></record> |
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subjects | Biological and Medical Physics Biomedical Engineering and Bioengineering Biophysics Blast Injuries - prevention & control Computation Computer based modeling Computer Simulation Engineering Eye Eye injuries Eye Injuries - prevention & control Eyes Eyes & eyesight Health risks Humans Injuries Mathematical models Models, Theoretical Orbit - anatomy & histology Original Paper Risk Risk Assessment - methods Risk factors Space life sciences Stresses Theoretical and Applied Mechanics |
title | Injury risk prediction from computational simulations of ocular blast loading |
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