Acyl Carrier Protein Cyanylation Delivers a Ketoacyl Synthase–Carrier Protein Cross-Link

Acyl carrier proteins (ACPs) are central hubs in polyketide and fatty acid biosynthetic pathways, but the fast motions of the ACP’s phosphopantetheine (Ppant) arm make its conformational dynamics difficult to capture using traditional spectroscopic approaches. Here we report that converting the term...

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Veröffentlicht in:	Biochemistry (Easton) 2017-05, Vol.56 (20), p.2533-2536
Hauptverfasser:	Thiele, Grace A. R, Friedman, Connie P, Tsai, Kathleen J. S, Beld, Joris, Londergan, Casey H, Charkoudian, Louise K
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyl Carrier Protein - chemistry Chromatography, Gel Cyanides - chemistry Escherichia coli Proteins - chemistry Polyketide Synthases - chemistry
Online-Zugang:	Volltext
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