Sonogashira diversification of unprotected halotryptophans, halotryptophan containing tripeptides; and generation of a new to nature bromo-natural product and its diversification in water

The blending together of synthetic chemistry with natural product biosynthesis represents a potentially powerful approach to synthesis; to enable this, further synthetic tools and methodologies are needed. To this end, we have explored the first Sonogashira cross-coupling to halotryptophans in water...

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Veröffentlicht in:	Chemical science (Cambridge) 2017-03, Vol.8 (3), p.2039-2046
Hauptverfasser:	Corr, M J, Sharma, S V, Pubill-Ulldemolins, C, Bown, R T, Poirot, P, Smith, D R M, Cartmell, C, Abou Fayad, A, Goss, R J M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosynthesis Blending Bromination Cross coupling Metabolites Natural products Precursors Synthesis (chemistry)
Online-Zugang:	Volltext
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