Participation of Antidiuretic Hormone (ADH) in Asthma Exacerbations Induced by Psychological Stress via PKA/PKC Signal Pathway in Airway-Related Vagal Preganglionic Neurons (AVPNs)

Aims: Present study was performed to examine whether ADH was implicated in psychological stress asthma and to explore the underlying molecular mechanism. Methods: We not only examined ADH levels in the cerebrospinal fluid (CSF) via radioimmunoassay, but also measured ADH receptor (ADHR) expression i...

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Veröffentlicht in:	Cellular physiology and biochemistry 2017-01, Vol.41 (6), p.2230-2241
Hauptverfasser:	Hou, Lili, Zhu, Lei, Zhang, Min, Zhang, Xingyi, Zhang, Guoqing, Liu, Zhenwei, Li, Qiang, Zhou, Xin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidiuretic hormone (ADH) Antidiuretic Hormone Receptor Antagonists - pharmacology Asthma Asthma - etiology Asthma - metabolism Carbazoles - pharmacology Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors Cyclic AMP-Dependent Protein Kinases - metabolism Cytokines Cytokines - metabolism Disease Models, Animal Eosinophils - cytology Eosinophils - metabolism Female Kinases Lymphocytes Mice Mice, Inbred BALB C Morpholines - pharmacology Neurons - metabolism Original Paper Ovalbumin - immunology PKA/PKC Protein Kinase C - antagonists & inhibitors Protein Kinase C - metabolism Protein Kinase Inhibitors - pharmacology Proteins Psychological stress Pyrroles - pharmacology Receptors, Vasopressin - chemistry Receptors, Vasopressin - metabolism Rodents Signal transduction Signal Transduction - drug effects Spiro Compounds - pharmacology Stress, Psychological Vasopressins - cerebrospinal fluid Vasopressins - metabolism
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