Systematic Comparison of False-Discovery-Rate-Controlling Strategies for Proteogenomic Search Using Spike-in Experiments

Proteogenomic searches are useful for novel peptide identification from tandem mass spectra. Usually, separate and multistage approaches are adopted to accurately control the false discovery rate (FDR) for proteogenomic search. Their performance on novel peptide identification has not been thoroughl...

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Veröffentlicht in:	Journal of proteome research 2017-06, Vol.16 (6), p.2231-2239
Hauptverfasser:	Li, Honglan, Park, Jonghun, Kim, Hyunwoo, Hwang, Kyu-Baek, Paek, Eunok
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Computer Simulation False Positive Reactions Humans Methods Models, Theoretical Peptides - analysis Proteogenomics - methods Tandem Mass Spectrometry
Online-Zugang:	Volltext
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