Association of vitamin D pathway SNPs and clinical response to interferon in a cohort of HBeAg-negative patients

Vitamin D modulates biological processes; an influence of vitamin D levels and genetic variants was identified concerning hepatitis B virus infection. We evaluated the role of some SNPs of vitamin D pathway genes in some clinical features of hepatitis B affected patients treated with pegylated inter...

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Veröffentlicht in:	Pharmacogenomics 2017-05, Vol.18 (7), p.651-661
Hauptverfasser:	Cusato, Jessica, Boglione, Lucio, De Nicolò, Amedeo, Imbornone, Rosaria, Cardellino, Chiara Simona, Ghisetti, Valeria, Carcieri, Chiara, Cariti, Giuseppe, Di Perri, Giovanni, D'Avolio, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anemia Antimicrobial agents Antiviral Agents - pharmacology Antiviral Agents - therapeutic use calcitriol Cancer Cell growth Cohort Studies Deoxyribonucleic acid DNA Female Gene expression genes Genetic diversity Genomics Genotype & phenotype Genotypes Hepatitis Hepatitis B Hepatitis B - blood Hepatitis B - drug therapy Hepatitis B - genetics Hepatitis B e antigen Hepatitis B e Antigens - blood Hepatitis B e Antigens - genetics Hepatitis B surface antigen Hepatology Humans Infections Interferon Interferon-alpha - pharmacology Interferon-alpha - therapeutic use Male Metabolites Middle Aged pharmacogenetics Polymorphism Polymorphism, Single Nucleotide - genetics Receptors, Calcitriol - blood Receptors, Calcitriol - genetics Retrospective Studies Signal Transduction - drug effects Signal Transduction - genetics Single-nucleotide polymorphism Treatment Outcome Vitamin D Vitamin D - blood Vitamin D - genetics Vitamin D receptors Vitamin deficiency
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