Drug release studies from lipid nanoparticles in physiological media by a new DSC method

[Display omitted] Lipid nanoparticles are an interesting parenteral delivery system for poorly water-soluble drugs. In order to approach physiological conditions when conducting release studies from such systems the release media should preferentially contain lipophilic acceptor compartments such as...

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Veröffentlicht in:	Journal of controlled release 2017-06, Vol.256, p.92-100
Hauptverfasser:	Roese, Elin, Bunjes, Heike
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Tocopherol - chemistry Animals Blood Calorimetry, Differential Scanning Canola Oil - chemistry Crystallization Differential scanning calorimetry Drug Carriers - chemistry Drug Liberation Drug release Emulsions Fenofibrate - chemistry Lactones - chemistry Lipid nanoparticles logP Nanoparticles - chemistry Physiological conditions Swine Triglycerides - chemistry Ubiquinone - analogs & derivatives Ubiquinone - chemistry
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