Comparison of the efficacy of IGIV-C, 10% (caprylate/chromatography) and IGIV-SD, 10% as replacement therapy in primary immune deficiency: A randomized double-blind trial

A novel method of large-scale chromatography has been developed to improve recovery and purity of immunoglobulin G (IgG) from pooled plasma. The current study compares safety, toxicity and efficacy of two intravenous immunoglobulin products: a novel formulation, IGIV caprylate/chromatography (IGIV-C...

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Veröffentlicht in:	International immunopharmacology 2003-09, Vol.3 (9), p.1325-1333
Hauptverfasser:	Roifman, Chaim M, Schroeder, Harry, Berger, Melvin, Sorensen, Ricardo, Ballow, Mark, Buckley, Rebecca H, Gewurz, Anita, Korenblat, Phillip, Sussman, Gordon, Lemm, Georg
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Analysis Biological and medical sciences caprylate Caprylates - adverse effects Caprylates - isolation & purification Caprylates - therapeutic use Child Child, Preschool Chromatography, Ion Exchange - methods Detergents Disease Susceptibility Double-Blind Method Female General pharmacology Humans IgG IGIV Immunoglobulin Immunoglobulins, Intravenous - adverse effects Immunoglobulins, Intravenous - isolation & purification Immunoglobulins, Intravenous - therapeutic use Immunologic Deficiency Syndromes - complications Immunologic Deficiency Syndromes - therapy Immunotherapy Incidence Infant Infection - epidemiology Infection - immunology Infection Control IVIG Male Medical sciences Middle Aged Pharmacology. Drug treatments Pneumonia - epidemiology Pneumonia - immunology Pneumonia - prevention & control Primary immunodeficiency Sinopulmonary infection Sinusitis Sinusitis - epidemiology Sinusitis - immunology Sinusitis - prevention & control Solvents Treatment Outcome Viral safety
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