Activation of protein kinase C inhibits retrograde transport of neurotrophins in mice

Retrograde axonal transport of neurotrophins from nerve terminal to cell body requires a number of key processes, including internalization of the receptor‐neurotrophin complex into vesicles and formation of multivesicular bodies and their transport along the axon. Previous studies have shown that e...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuroscience research 2003-04, Vol.72 (2), p.203-210
Hauptverfasser:	Ozsarac, Nesrin, Weible 2nd, Michael, Reynolds, Anna J., Hendry, Ian A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - drug effects Animals Axonal Transport - drug effects Axonal Transport - physiology Cell Survival - drug effects Enzyme Activators - pharmacology Enzyme Inhibitors - pharmacology Eye - innervation Eye - metabolism Growth Cones - drug effects Indoles - pharmacology Male Mice Mice, Inbred BALB C Nerve Growth Factors - drug effects Nerve Growth Factors - metabolism Neurons, Afferent - drug effects Neurons, Afferent - metabolism NGF NT4 p75NTR phorbol esters Presynaptic Terminals - drug effects Protein Kinase C - antagonists & inhibitors Protein Kinase C - drug effects Protein Kinase C - metabolism Receptor, Nerve Growth Factor - metabolism Receptor, trkA - metabolism Superior Cervical Ganglion - metabolism Sympathetic Nervous System - metabolism Tetradecanoylphorbol Acetate - pharmacology Trigeminal Ganglion - metabolism TrkA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!