Releasing the potential power of terpene synthases by a robust precursor supply platform

Terpenoids represent the largest family of natural products. Their structural diversity is largely due to variable skeletons generated by terpene synthases. However, terpene skeletons found in nature are much more than those generated from known terpene synthases. Most promiscuous terpene synthases...

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Veröffentlicht in:	Metabolic engineering 2017-07, Vol.42, p.1-8
Hauptverfasser:	Bian, Guangkai, Han, Yichao, Hou, Anwei, Yuan, Yujie, Liu, Xinhua, Deng, Zixin, Liu, Tiangang
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkyl and Aryl Transferases - chemistry Alkyl and Aryl Transferases - genetics Bacterial Proteins - chemistry Bacterial Proteins - genetics Combinatorial biosynthesis Point Mutation Polyisoprenyl Phosphates - chemistry Precursor supply Promiscuous Protein engineering Skeleton reframing Terpene synthases Terpenoids
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