A population‐based study of the association between dysglycaemia and hearing loss in middle age
Aims To investigate the independent associations between hearing loss and dysglycaemia in a sample of middle‐aged adults, including separate analysis of those aged < 60 years. Methods The first 2023 participants in the cross‐sectional Busselton Health Ageing Survey were assessed for hearing loss...
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| Veröffentlicht in: | Diabetic medicine 2017-05, Vol.34 (5), p.683-690 |
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| creator | Sommer, J. Brenann‐Jones, C. G. Eikelboom, R. H. Hunter, M. Davis, W. A. Atlas, M. D. Davis, T. M. E. |
| description | Aims
To investigate the independent associations between hearing loss and dysglycaemia in a sample of middle‐aged adults, including separate analysis of those aged < 60 years.
Methods
The first 2023 participants in the cross‐sectional Busselton Health Ageing Survey were assessed for hearing loss ≥ 26 dB (better ear) for four‐frequency average (4FA) of pure‐tone thresholds at 500, 1000, 2000 and 4000 Hz, and high‐frequency average (HFA) of pure‐tone thresholds at 4000 and 8000 Hz.
Results
Valid data from 1864 participants in the Busselton Health Ageing Survey [92.1%; mean ± sd age 56.2 ± 5.5 years, 46.0% men, 120 (7.0%) with diabetes, 274 (14.7%) with prediabetes] were analysed, of whom 103 (5.5%) had four‐frequency average hearing loss and 561 (30.1%) had high‐frequency average hearing loss. In multivariable analyses, glycaemic status was not independently associated with four‐frequency or high‐frequency average hearing loss. In the 1286 participants aged < 60 years, there was no relationship between dysglycaemia and high‐frequency average hearing loss, but the prevalence of four‐frequency average hearing loss increased from 2.3% (95% CI 1.5–3.4) in participants with normoglycaemia to 5.7% (95% CI 3.0–10.6) in those with prediabetes and 10.2% (4.2–21.5) in those with diabetes (trend P = 0.003). In multivariable analysis with normoglycaemia as reference, the odds ratios for four‐frequency average hearing loss were 2.84 (95% CI 1.29–6.27) for prediabetes and 5.93 (95% CI 1.67–21.05) for diabetes (P ≤ 0.01) in the < 60 year age group.
Conclusions
There was progressively increasing mid‐range hearing loss with worsening glucose tolerance in younger individuals, suggesting dysglycaemia‐associated early‐onset presbycusis.
What's new?
There have been few population‐based studies of hearing loss in diabetes in well characterized participants, and none in prediabetes.
In participants in the Busselton Health Ageing Survey aged < 60 years, increasing dysglycaemia was associated with increasing mid‐range hearing loss after adjustment for other recognized risk factors for hearing impairment
There was no relationship between dysglycaemia and hearing loss in participants aged ≥ 60 years.
Abnormal glucose tolerance may independently accelerate the onset of presbycusis in younger people with diabetes. |
| doi_str_mv | 10.1111/dme.13320 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1891883212</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1862937897</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3860-cfe197d1a0cd4324a0134fe9c0dd67248e9373d7b49d4120684f25c1b6fb6e03</originalsourceid><addsrcrecordid>eNqN0ctKxDAUBuAgio6jC19AAm50UScnybTJUryD4sZ9SZPTMdLL2LRIdz6Cz-iTGB11IQieTTZffjjnJ2QP2DHEmbkaj0EIztbIBGQqk7nUsE4mLJM8ESyDLbIdwiNjwLXQm2SLKxBzBmxCzAldtsuhMr1vm7eX18IEdDT0gxtpW9L-AakJobX-E9AC-2fEhroxLKrRGqy9oaZx9AFN55sFrdoQqG9o7Z2r4t8F7pCN0lQBd7_eKbm_OL8_vUpu7i6vT09uEitUyhJbIujMgWHWScGlYSBkidoy59KMS4VaZMJlhdROAmepkiWfWyjSskiRiSk5XMUuu_ZpwNDntQ8Wq8o02A4hB6VBKcGB_4Om8U6Z0lmkB7_oYzt0TdwjKqU0E2oOUR2tlO3i-h2W-bLztenGHFj-0VAeG8o_G4p2_ytxKGp0P_K7kghmK_DsKxz_TsrPbs9Xke82P5nf</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1888903851</pqid></control><display><type>article</type><title>A population‐based study of the association between dysglycaemia and hearing loss in middle age</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Sommer, J. ; Brenann‐Jones, C. G. ; Eikelboom, R. H. ; Hunter, M. ; Davis, W. A. ; Atlas, M. D. ; Davis, T. M. E.</creator><creatorcontrib>Sommer, J. ; Brenann‐Jones, C. G. ; Eikelboom, R. H. ; Hunter, M. ; Davis, W. A. ; Atlas, M. D. ; Davis, T. M. E.</creatorcontrib><description>Aims
To investigate the independent associations between hearing loss and dysglycaemia in a sample of middle‐aged adults, including separate analysis of those aged < 60 years.
Methods
The first 2023 participants in the cross‐sectional Busselton Health Ageing Survey were assessed for hearing loss ≥ 26 dB (better ear) for four‐frequency average (4FA) of pure‐tone thresholds at 500, 1000, 2000 and 4000 Hz, and high‐frequency average (HFA) of pure‐tone thresholds at 4000 and 8000 Hz.
Results
Valid data from 1864 participants in the Busselton Health Ageing Survey [92.1%; mean ± sd age 56.2 ± 5.5 years, 46.0% men, 120 (7.0%) with diabetes, 274 (14.7%) with prediabetes] were analysed, of whom 103 (5.5%) had four‐frequency average hearing loss and 561 (30.1%) had high‐frequency average hearing loss. In multivariable analyses, glycaemic status was not independently associated with four‐frequency or high‐frequency average hearing loss. In the 1286 participants aged < 60 years, there was no relationship between dysglycaemia and high‐frequency average hearing loss, but the prevalence of four‐frequency average hearing loss increased from 2.3% (95% CI 1.5–3.4) in participants with normoglycaemia to 5.7% (95% CI 3.0–10.6) in those with prediabetes and 10.2% (4.2–21.5) in those with diabetes (trend P = 0.003). In multivariable analysis with normoglycaemia as reference, the odds ratios for four‐frequency average hearing loss were 2.84 (95% CI 1.29–6.27) for prediabetes and 5.93 (95% CI 1.67–21.05) for diabetes (P ≤ 0.01) in the < 60 year age group.
Conclusions
There was progressively increasing mid‐range hearing loss with worsening glucose tolerance in younger individuals, suggesting dysglycaemia‐associated early‐onset presbycusis.
What's new?
There have been few population‐based studies of hearing loss in diabetes in well characterized participants, and none in prediabetes.
In participants in the Busselton Health Ageing Survey aged < 60 years, increasing dysglycaemia was associated with increasing mid‐range hearing loss after adjustment for other recognized risk factors for hearing impairment
There was no relationship between dysglycaemia and hearing loss in participants aged ≥ 60 years.
Abnormal glucose tolerance may independently accelerate the onset of presbycusis in younger people with diabetes.</description><identifier>ISSN: 0742-3071</identifier><identifier>EISSN: 1464-5491</identifier><identifier>DOI: 10.1111/dme.13320</identifier><identifier>PMID: 28135010</identifier><identifier>CODEN: DIMEEV</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Age of Onset ; Aging ; Aging - blood ; Aging - physiology ; Blood Glucose - metabolism ; Cross-Sectional Studies ; Diabetes ; Diabetes Mellitus, Type 2 - blood ; Diabetes Mellitus, Type 2 - complications ; Diabetes Mellitus, Type 2 - epidemiology ; Female ; Glucose Metabolism Disorders - blood ; Glucose Metabolism Disorders - complications ; Glucose Metabolism Disorders - epidemiology ; Hearing loss ; Hearing Loss - blood ; Hearing Loss - epidemiology ; Hearing Loss - etiology ; Hearing protection ; Humans ; Male ; Middle Aged ; Prediabetic State - blood ; Prediabetic State - complications ; Prediabetic State - epidemiology ; Presbycusis - blood ; Presbycusis - epidemiology ; Prevalence</subject><ispartof>Diabetic medicine, 2017-05, Vol.34 (5), p.683-690</ispartof><rights>2017 Diabetes UK</rights><rights>2017 Diabetes UK.</rights><rights>Diabetic Medicine © 2017 Diabetes UK</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3860-cfe197d1a0cd4324a0134fe9c0dd67248e9373d7b49d4120684f25c1b6fb6e03</citedby><cites>FETCH-LOGICAL-c3860-cfe197d1a0cd4324a0134fe9c0dd67248e9373d7b49d4120684f25c1b6fb6e03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fdme.13320$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fdme.13320$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28135010$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sommer, J.</creatorcontrib><creatorcontrib>Brenann‐Jones, C. G.</creatorcontrib><creatorcontrib>Eikelboom, R. H.</creatorcontrib><creatorcontrib>Hunter, M.</creatorcontrib><creatorcontrib>Davis, W. A.</creatorcontrib><creatorcontrib>Atlas, M. D.</creatorcontrib><creatorcontrib>Davis, T. M. E.</creatorcontrib><title>A population‐based study of the association between dysglycaemia and hearing loss in middle age</title><title>Diabetic medicine</title><addtitle>Diabet Med</addtitle><description>Aims
To investigate the independent associations between hearing loss and dysglycaemia in a sample of middle‐aged adults, including separate analysis of those aged < 60 years.
Methods
The first 2023 participants in the cross‐sectional Busselton Health Ageing Survey were assessed for hearing loss ≥ 26 dB (better ear) for four‐frequency average (4FA) of pure‐tone thresholds at 500, 1000, 2000 and 4000 Hz, and high‐frequency average (HFA) of pure‐tone thresholds at 4000 and 8000 Hz.
Results
Valid data from 1864 participants in the Busselton Health Ageing Survey [92.1%; mean ± sd age 56.2 ± 5.5 years, 46.0% men, 120 (7.0%) with diabetes, 274 (14.7%) with prediabetes] were analysed, of whom 103 (5.5%) had four‐frequency average hearing loss and 561 (30.1%) had high‐frequency average hearing loss. In multivariable analyses, glycaemic status was not independently associated with four‐frequency or high‐frequency average hearing loss. In the 1286 participants aged < 60 years, there was no relationship between dysglycaemia and high‐frequency average hearing loss, but the prevalence of four‐frequency average hearing loss increased from 2.3% (95% CI 1.5–3.4) in participants with normoglycaemia to 5.7% (95% CI 3.0–10.6) in those with prediabetes and 10.2% (4.2–21.5) in those with diabetes (trend P = 0.003). In multivariable analysis with normoglycaemia as reference, the odds ratios for four‐frequency average hearing loss were 2.84 (95% CI 1.29–6.27) for prediabetes and 5.93 (95% CI 1.67–21.05) for diabetes (P ≤ 0.01) in the < 60 year age group.
Conclusions
There was progressively increasing mid‐range hearing loss with worsening glucose tolerance in younger individuals, suggesting dysglycaemia‐associated early‐onset presbycusis.
What's new?
There have been few population‐based studies of hearing loss in diabetes in well characterized participants, and none in prediabetes.
In participants in the Busselton Health Ageing Survey aged < 60 years, increasing dysglycaemia was associated with increasing mid‐range hearing loss after adjustment for other recognized risk factors for hearing impairment
There was no relationship between dysglycaemia and hearing loss in participants aged ≥ 60 years.
Abnormal glucose tolerance may independently accelerate the onset of presbycusis in younger people with diabetes.</description><subject>Age of Onset</subject><subject>Aging</subject><subject>Aging - blood</subject><subject>Aging - physiology</subject><subject>Blood Glucose - metabolism</subject><subject>Cross-Sectional Studies</subject><subject>Diabetes</subject><subject>Diabetes Mellitus, Type 2 - blood</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Female</subject><subject>Glucose Metabolism Disorders - blood</subject><subject>Glucose Metabolism Disorders - complications</subject><subject>Glucose Metabolism Disorders - epidemiology</subject><subject>Hearing loss</subject><subject>Hearing Loss - blood</subject><subject>Hearing Loss - epidemiology</subject><subject>Hearing Loss - etiology</subject><subject>Hearing protection</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prediabetic State - blood</subject><subject>Prediabetic State - complications</subject><subject>Prediabetic State - epidemiology</subject><subject>Presbycusis - blood</subject><subject>Presbycusis - epidemiology</subject><subject>Prevalence</subject><issn>0742-3071</issn><issn>1464-5491</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0ctKxDAUBuAgio6jC19AAm50UScnybTJUryD4sZ9SZPTMdLL2LRIdz6Cz-iTGB11IQieTTZffjjnJ2QP2DHEmbkaj0EIztbIBGQqk7nUsE4mLJM8ESyDLbIdwiNjwLXQm2SLKxBzBmxCzAldtsuhMr1vm7eX18IEdDT0gxtpW9L-AakJobX-E9AC-2fEhroxLKrRGqy9oaZx9AFN55sFrdoQqG9o7Z2r4t8F7pCN0lQBd7_eKbm_OL8_vUpu7i6vT09uEitUyhJbIujMgWHWScGlYSBkidoy59KMS4VaZMJlhdROAmepkiWfWyjSskiRiSk5XMUuu_ZpwNDntQ8Wq8o02A4hB6VBKcGB_4Om8U6Z0lmkB7_oYzt0TdwjKqU0E2oOUR2tlO3i-h2W-bLztenGHFj-0VAeG8o_G4p2_ytxKGp0P_K7kghmK_DsKxz_TsrPbs9Xke82P5nf</recordid><startdate>201705</startdate><enddate>201705</enddate><creator>Sommer, J.</creator><creator>Brenann‐Jones, C. G.</creator><creator>Eikelboom, R. H.</creator><creator>Hunter, M.</creator><creator>Davis, W. A.</creator><creator>Atlas, M. D.</creator><creator>Davis, T. M. E.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>201705</creationdate><title>A population‐based study of the association between dysglycaemia and hearing loss in middle age</title><author>Sommer, J. ; Brenann‐Jones, C. G. ; Eikelboom, R. H. ; Hunter, M. ; Davis, W. A. ; Atlas, M. D. ; Davis, T. M. E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3860-cfe197d1a0cd4324a0134fe9c0dd67248e9373d7b49d4120684f25c1b6fb6e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Age of Onset</topic><topic>Aging</topic><topic>Aging - blood</topic><topic>Aging - physiology</topic><topic>Blood Glucose - metabolism</topic><topic>Cross-Sectional Studies</topic><topic>Diabetes</topic><topic>Diabetes Mellitus, Type 2 - blood</topic><topic>Diabetes Mellitus, Type 2 - complications</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Female</topic><topic>Glucose Metabolism Disorders - blood</topic><topic>Glucose Metabolism Disorders - complications</topic><topic>Glucose Metabolism Disorders - epidemiology</topic><topic>Hearing loss</topic><topic>Hearing Loss - blood</topic><topic>Hearing Loss - epidemiology</topic><topic>Hearing Loss - etiology</topic><topic>Hearing protection</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prediabetic State - blood</topic><topic>Prediabetic State - complications</topic><topic>Prediabetic State - epidemiology</topic><topic>Presbycusis - blood</topic><topic>Presbycusis - epidemiology</topic><topic>Prevalence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sommer, J.</creatorcontrib><creatorcontrib>Brenann‐Jones, C. G.</creatorcontrib><creatorcontrib>Eikelboom, R. H.</creatorcontrib><creatorcontrib>Hunter, M.</creatorcontrib><creatorcontrib>Davis, W. A.</creatorcontrib><creatorcontrib>Atlas, M. D.</creatorcontrib><creatorcontrib>Davis, T. M. E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Diabetic medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sommer, J.</au><au>Brenann‐Jones, C. G.</au><au>Eikelboom, R. H.</au><au>Hunter, M.</au><au>Davis, W. A.</au><au>Atlas, M. D.</au><au>Davis, T. M. E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A population‐based study of the association between dysglycaemia and hearing loss in middle age</atitle><jtitle>Diabetic medicine</jtitle><addtitle>Diabet Med</addtitle><date>2017-05</date><risdate>2017</risdate><volume>34</volume><issue>5</issue><spage>683</spage><epage>690</epage><pages>683-690</pages><issn>0742-3071</issn><eissn>1464-5491</eissn><coden>DIMEEV</coden><abstract>Aims
To investigate the independent associations between hearing loss and dysglycaemia in a sample of middle‐aged adults, including separate analysis of those aged < 60 years.
Methods
The first 2023 participants in the cross‐sectional Busselton Health Ageing Survey were assessed for hearing loss ≥ 26 dB (better ear) for four‐frequency average (4FA) of pure‐tone thresholds at 500, 1000, 2000 and 4000 Hz, and high‐frequency average (HFA) of pure‐tone thresholds at 4000 and 8000 Hz.
Results
Valid data from 1864 participants in the Busselton Health Ageing Survey [92.1%; mean ± sd age 56.2 ± 5.5 years, 46.0% men, 120 (7.0%) with diabetes, 274 (14.7%) with prediabetes] were analysed, of whom 103 (5.5%) had four‐frequency average hearing loss and 561 (30.1%) had high‐frequency average hearing loss. In multivariable analyses, glycaemic status was not independently associated with four‐frequency or high‐frequency average hearing loss. In the 1286 participants aged < 60 years, there was no relationship between dysglycaemia and high‐frequency average hearing loss, but the prevalence of four‐frequency average hearing loss increased from 2.3% (95% CI 1.5–3.4) in participants with normoglycaemia to 5.7% (95% CI 3.0–10.6) in those with prediabetes and 10.2% (4.2–21.5) in those with diabetes (trend P = 0.003). In multivariable analysis with normoglycaemia as reference, the odds ratios for four‐frequency average hearing loss were 2.84 (95% CI 1.29–6.27) for prediabetes and 5.93 (95% CI 1.67–21.05) for diabetes (P ≤ 0.01) in the < 60 year age group.
Conclusions
There was progressively increasing mid‐range hearing loss with worsening glucose tolerance in younger individuals, suggesting dysglycaemia‐associated early‐onset presbycusis.
What's new?
There have been few population‐based studies of hearing loss in diabetes in well characterized participants, and none in prediabetes.
In participants in the Busselton Health Ageing Survey aged < 60 years, increasing dysglycaemia was associated with increasing mid‐range hearing loss after adjustment for other recognized risk factors for hearing impairment
There was no relationship between dysglycaemia and hearing loss in participants aged ≥ 60 years.
Abnormal glucose tolerance may independently accelerate the onset of presbycusis in younger people with diabetes.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>28135010</pmid><doi>10.1111/dme.13320</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0742-3071 |
| ispartof | Diabetic medicine, 2017-05, Vol.34 (5), p.683-690 |
| issn | 0742-3071 1464-5491 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Age of Onset Aging Aging - blood Aging - physiology Blood Glucose - metabolism Cross-Sectional Studies Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - epidemiology Female Glucose Metabolism Disorders - blood Glucose Metabolism Disorders - complications Glucose Metabolism Disorders - epidemiology Hearing loss Hearing Loss - blood Hearing Loss - epidemiology Hearing Loss - etiology Hearing protection Humans Male Middle Aged Prediabetic State - blood Prediabetic State - complications Prediabetic State - epidemiology Presbycusis - blood Presbycusis - epidemiology Prevalence |
| title | A population‐based study of the association between dysglycaemia and hearing loss in middle age |
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