Regulation of Pancreatic [alpha]-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro

Increased expression of bone morphogenetic proteins (BMPs) in several tissues is associated with inflammation and type 2 diabetes mellitus. BMP2 and BMP4 mRNA expression is increased in pancreatic islets from db/db mice and [beta]-cell proliferation and function are inhibited by BMP4. The effect of...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2016-10, Vol.157 (10), p.3809-3820
Hauptverfasser:	Nielsen, Sofie Sylvest, Christensen, Gitte Lund, Holst, Jens Juul, Billestrup, Nils
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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