De novo DQ donor‐specific antibodies are associated with worse outcomes compared to non‐DQ de novo donor‐specific antibodies following heart transplantation

Background Antibody‐mediated rejection (AMR) resulting from de novo donor‐specific antibodies (dnDSA) leads to adverse outcomes following heart transplantation (HTx). It remains unclear what role dnDSA to specific HLA antigens play in adverse outcomes. This study compares outcomes in patients develo...

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Veröffentlicht in:	Clinical transplantation 2017-04, Vol.31 (4), p.np-n/a
Hauptverfasser:	Cole, Robert Townsend, Gandhi, Jonathan, Bray, Robert A., Gebel, Howard M., Morris, Alanna, McCue, Andrew, Yin, Michael, Laskar, S. Raja, Book, Wendy, Jokhadar, Maan, Smith, Andrew, Nguyen, Duc, Vega, J. David, Gupta, Divya
Format:	Artikel
Sprache:	eng
Schlagworte:	antibody‐mediated rejection donor‐specific antibodies Female Follow-Up Studies Graft Rejection - etiology Graft Rejection - pathology Graft Survival heart transplantation Heart Transplantation - adverse effects HLA-DQ Antigens - immunology Humans Isoantibodies - blood Isoantibodies - immunology Male Middle Aged Postoperative Complications Prognosis Retrospective Studies Risk Factors Tissue Donors
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