Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice

Fetal and adult Leydig cells develop in mammalian prenatal and postnatal testes, respectively. In mice, fetal Leydig cells (FLCs) emerge in the interstitial space of the testis at embryonic day 12.5 and thereafter increase in number, possibly through differentiation from progenitor cells. However, t...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2016-03, Vol.157 (3), p.1222-1233
Hauptverfasser:	Inoue, Miki, Shima, Yuichi, Miyabayashi, Kanako, Tokunaga, Kaori, Sato, Tetsuya, Baba, Takashi, Ohkawa, Yasuyuki, Akiyama, Haruhiko, Suyama, Mikita, Morohashi, Ken-ichirou
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Cells (biology) Citric Acid Cycle - genetics Differentiation Energy metabolism Energy Metabolism - genetics Fetus - metabolism Fetuses Flow cytometry Fluorescence Gene Expression Profiling Gene Expression Regulation, Developmental Genes Glycolysis Glycolysis - genetics Gonadal Steroid Hormones - biosynthesis Green fluorescent protein Green Fluorescent Proteins - genetics Growth factors Immunohistochemistry Leydig cells Leydig Cells - cytology Leydig Cells - metabolism Male Mice Mice, Transgenic Progenitor cells Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Signal Transduction - genetics Stem Cells - cytology Stem Cells - metabolism Steroidogenesis Testes Transcriptomes Transgenic mice
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